Grape Pomace: A Review of Its Bioactive Phenolic Compounds, Health Benefits, and Applications

The wine industry generates high amounts of waste, posing current environmental and economic sustainability challenges. Grape pomace, mainly composed of seeds, skins, and stalks, contains significant amounts of bioactive compounds and constitutes the main solid residue of this industry. Various stra...

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Main Authors: Janice da Conceição Lopes, Joana Madureira, Fernanda M. A. Margaça, Sandra Cabo Verde
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/30/2/362
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author Janice da Conceição Lopes
Joana Madureira
Fernanda M. A. Margaça
Sandra Cabo Verde
author_facet Janice da Conceição Lopes
Joana Madureira
Fernanda M. A. Margaça
Sandra Cabo Verde
author_sort Janice da Conceição Lopes
collection DOAJ
description The wine industry generates high amounts of waste, posing current environmental and economic sustainability challenges. Grape pomace, mainly composed of seeds, skins, and stalks, contains significant amounts of bioactive compounds and constitutes the main solid residue of this industry. Various strategies are being explored for its valorization, from a circular economy perspective. This review provides an updated overview of the composition of grape pomace from winemaking, highlighting sustainable methodologies for extracting phenolic compounds and their potential health benefits, including antioxidant, antimicrobial, antidiabetic, cardioprotective, antiproliferative, anti-aging, and gut health properties. Furthermore, this review explores the potential applications of this agro-industrial waste and its extractable compounds across the food, cosmetic, and pharmaceutical sectors.
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publishDate 2025-01-01
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series Molecules
spelling doaj-art-8d13f40c1a4f42f38162ceb6bc71358a2025-01-24T13:43:46ZengMDPI AGMolecules1420-30492025-01-0130236210.3390/molecules30020362Grape Pomace: A Review of Its Bioactive Phenolic Compounds, Health Benefits, and ApplicationsJanice da Conceição Lopes0Joana Madureira1Fernanda M. A. Margaça2Sandra Cabo Verde3Centro de Ciências e Tecnologias Nucleares (C2TN), Instituto Superior Técnico, Universidade de Lisboa, E.N. 10 ao km 139.7, 2695-066 Bobadela LRS, PortugalCentro de Ciências e Tecnologias Nucleares (C2TN), Instituto Superior Técnico, Universidade de Lisboa, E.N. 10 ao km 139.7, 2695-066 Bobadela LRS, PortugalCentro de Ciências e Tecnologias Nucleares (C2TN), Instituto Superior Técnico, Universidade de Lisboa, E.N. 10 ao km 139.7, 2695-066 Bobadela LRS, PortugalCentro de Ciências e Tecnologias Nucleares (C2TN), Instituto Superior Técnico, Universidade de Lisboa, E.N. 10 ao km 139.7, 2695-066 Bobadela LRS, PortugalThe wine industry generates high amounts of waste, posing current environmental and economic sustainability challenges. Grape pomace, mainly composed of seeds, skins, and stalks, contains significant amounts of bioactive compounds and constitutes the main solid residue of this industry. Various strategies are being explored for its valorization, from a circular economy perspective. This review provides an updated overview of the composition of grape pomace from winemaking, highlighting sustainable methodologies for extracting phenolic compounds and their potential health benefits, including antioxidant, antimicrobial, antidiabetic, cardioprotective, antiproliferative, anti-aging, and gut health properties. Furthermore, this review explores the potential applications of this agro-industrial waste and its extractable compounds across the food, cosmetic, and pharmaceutical sectors.https://www.mdpi.com/1420-3049/30/2/362grape marcbioactive compoundsextraction methodshealth benefitsagro-wastes valorizationsustainability
spellingShingle Janice da Conceição Lopes
Joana Madureira
Fernanda M. A. Margaça
Sandra Cabo Verde
Grape Pomace: A Review of Its Bioactive Phenolic Compounds, Health Benefits, and Applications
Molecules
grape marc
bioactive compounds
extraction methods
health benefits
agro-wastes valorization
sustainability
title Grape Pomace: A Review of Its Bioactive Phenolic Compounds, Health Benefits, and Applications
title_full Grape Pomace: A Review of Its Bioactive Phenolic Compounds, Health Benefits, and Applications
title_fullStr Grape Pomace: A Review of Its Bioactive Phenolic Compounds, Health Benefits, and Applications
title_full_unstemmed Grape Pomace: A Review of Its Bioactive Phenolic Compounds, Health Benefits, and Applications
title_short Grape Pomace: A Review of Its Bioactive Phenolic Compounds, Health Benefits, and Applications
title_sort grape pomace a review of its bioactive phenolic compounds health benefits and applications
topic grape marc
bioactive compounds
extraction methods
health benefits
agro-wastes valorization
sustainability
url https://www.mdpi.com/1420-3049/30/2/362
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AT fernandamamargaca grapepomaceareviewofitsbioactivephenoliccompoundshealthbenefitsandapplications
AT sandracaboverde grapepomaceareviewofitsbioactivephenoliccompoundshealthbenefitsandapplications