Vitamin D and HbA1c levels in newly diagnosed type 2 diabetes mellitus

Background: This study examined the correlation between 25-hydroxyvitamin D [25(OH)D] and glycated hemoglobin (HbA1c) levels in male and female patients diagnosed with type 2 diabetes mellitus (T2DM). Design: Hospital-based cross-sectional study. Materials and Methods: This study was conducted in th...

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Main Authors: Baligumba Ramu Kiran, Venoor Shreyas Kumar, Giri Premkumar Preeti, Venoor Ajith Kumar, Bheemappa Raja Vikas
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2024-12-01
Series:MGM Journal of Medical Sciences
Subjects:
Online Access:https://doi.org/10.4103/mgmj.mgmj_141_23
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author Baligumba Ramu Kiran
Venoor Shreyas Kumar
Giri Premkumar Preeti
Venoor Ajith Kumar
Bheemappa Raja Vikas
author_facet Baligumba Ramu Kiran
Venoor Shreyas Kumar
Giri Premkumar Preeti
Venoor Ajith Kumar
Bheemappa Raja Vikas
author_sort Baligumba Ramu Kiran
collection DOAJ
description Background: This study examined the correlation between 25-hydroxyvitamin D [25(OH)D] and glycated hemoglobin (HbA1c) levels in male and female patients diagnosed with type 2 diabetes mellitus (T2DM). Design: Hospital-based cross-sectional study. Materials and Methods: This study was conducted in the Department of General Medicine at Rajarajeswari Medical College and Hospital, Bengaluru, Karnataka, India, with the Institutional Ethics Committee approval. Each participant admitted to the hospital as an inpatient or outpatient underwent a thorough medical history review, physical examination, and relevant diagnostic tests. Vital signs, including pulse rate and blood pressure, were recorded as part of the general examination. Additionally, detailed assessments and investigations evaluated participants for potential vitamin D deficiency. Results: The mean age of participants was 59.46 ± 11.06 years, with an observed trend of increasing vitamin D deficiency with age. No significant association was found between gender and HbA1c or vitamin D levels. The average HbA1c level was 9.75% ± 2.05, while the mean vitamin D level was 23.44 ng/mL ± 8.26. A negative correlation was identified between serum vitamin D and HbA1c levels, with a correlation coefficient of −0.53 and a P value of <0.01. Conclusion: The study confirmed an association between vitamin D deficiency and elevated HbA1c levels in T2DM patients, with variations observed between male and female subjects.
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spelling doaj-art-8d10f8019b9146acacbeb3ccb11e99212025-01-17T10:55:33ZengWolters Kluwer Medknow PublicationsMGM Journal of Medical Sciences2347-79462347-79622024-12-0111472272710.4103/mgmj.mgmj_141_23Vitamin D and HbA1c levels in newly diagnosed type 2 diabetes mellitusBaligumba Ramu KiranVenoor Shreyas KumarGiri Premkumar PreetiVenoor Ajith KumarBheemappa Raja VikasBackground: This study examined the correlation between 25-hydroxyvitamin D [25(OH)D] and glycated hemoglobin (HbA1c) levels in male and female patients diagnosed with type 2 diabetes mellitus (T2DM). Design: Hospital-based cross-sectional study. Materials and Methods: This study was conducted in the Department of General Medicine at Rajarajeswari Medical College and Hospital, Bengaluru, Karnataka, India, with the Institutional Ethics Committee approval. Each participant admitted to the hospital as an inpatient or outpatient underwent a thorough medical history review, physical examination, and relevant diagnostic tests. Vital signs, including pulse rate and blood pressure, were recorded as part of the general examination. Additionally, detailed assessments and investigations evaluated participants for potential vitamin D deficiency. Results: The mean age of participants was 59.46 ± 11.06 years, with an observed trend of increasing vitamin D deficiency with age. No significant association was found between gender and HbA1c or vitamin D levels. The average HbA1c level was 9.75% ± 2.05, while the mean vitamin D level was 23.44 ng/mL ± 8.26. A negative correlation was identified between serum vitamin D and HbA1c levels, with a correlation coefficient of −0.53 and a P value of <0.01. Conclusion: The study confirmed an association between vitamin D deficiency and elevated HbA1c levels in T2DM patients, with variations observed between male and female subjects.https://doi.org/10.4103/mgmj.mgmj_141_23glycated hemoglobintype 2 diabetes mellitus25-hydroxyvitamin d
spellingShingle Baligumba Ramu Kiran
Venoor Shreyas Kumar
Giri Premkumar Preeti
Venoor Ajith Kumar
Bheemappa Raja Vikas
Vitamin D and HbA1c levels in newly diagnosed type 2 diabetes mellitus
MGM Journal of Medical Sciences
glycated hemoglobin
type 2 diabetes mellitus
25-hydroxyvitamin d
title Vitamin D and HbA1c levels in newly diagnosed type 2 diabetes mellitus
title_full Vitamin D and HbA1c levels in newly diagnosed type 2 diabetes mellitus
title_fullStr Vitamin D and HbA1c levels in newly diagnosed type 2 diabetes mellitus
title_full_unstemmed Vitamin D and HbA1c levels in newly diagnosed type 2 diabetes mellitus
title_short Vitamin D and HbA1c levels in newly diagnosed type 2 diabetes mellitus
title_sort vitamin d and hba1c levels in newly diagnosed type 2 diabetes mellitus
topic glycated hemoglobin
type 2 diabetes mellitus
25-hydroxyvitamin d
url https://doi.org/10.4103/mgmj.mgmj_141_23
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AT giripremkumarpreeti vitamindandhba1clevelsinnewlydiagnosedtype2diabetesmellitus
AT venoorajithkumar vitamindandhba1clevelsinnewlydiagnosedtype2diabetesmellitus
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