Assessment of High Frequency Imaging and Doppler System for the Measurements of the Radial Artery Flow-Mediated Dilation
Objectives: In the article we describe the new, high frequency, 20 MHz scanning/Doppler probe designed to measure the flow mediated dilation (FMD) and shear rate (SR) close to the radial artery wall. Methods: We compare two US scanning systems, standard vascular modality working below 12 MHz and...
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| Format: | Article |
| Language: | English |
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Institute of Fundamental Technological Research Polish Academy of Sciences
2019-07-01
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| Series: | Archives of Acoustics |
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| Online Access: | https://acoustics.ippt.pan.pl/index.php/aa/article/view/2590 |
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| author | Andrzej NOWICKI Barbara GAMBIN Wojciech SECOMSKI Zbigniew TRAWŃSKI Michał SZUBIELSKI Ryszard TYMKIEWICZ Robert OLSZEWSKI |
| author_facet | Andrzej NOWICKI Barbara GAMBIN Wojciech SECOMSKI Zbigniew TRAWŃSKI Michał SZUBIELSKI Ryszard TYMKIEWICZ Robert OLSZEWSKI |
| author_sort | Andrzej NOWICKI |
| collection | DOAJ |
| description | Objectives: In the article we describe the new, high frequency, 20 MHz scanning/Doppler probe designed to measure the flow mediated dilation (FMD) and shear rate (SR) close to the radial artery wall.
Methods: We compare two US scanning systems, standard vascular modality working below 12 MHz and high frequency 20 MHz system designed for FMD and SR measurements. Axial resolutions of both systems were compared by imaging of two closely spaced food plastic foils immersed in water and by measuring systolic/diastolic diameter changes in the radial artery. The sensitivities of Doppler modalities were also determined. The diagnostic potential of a high frequency system in measurements of FMD and SR was studied in vivo, in two groups of subjects, 12 healthy volunteers and 14 patients with stable coronary artery disease (CAD).
Results: Over three times better axial resolution was demonstrated for a high frequency system. Also, the sensitivity of the external single transducer 20 MHz pulse Doppler proved to be over 20 dB better (in terms of a signal-to-noise ratio) than the pulse Doppler incorporated into the linear array. Statistically significant differences in FMD and FMD/SR values for healthy volunteers and CAD patients were confirmed, p-values < 0:05. The areas under Receiver Operating Characteristic (ROC) curves for FMD and FMD/SR for the prediction CAD had the values of 0.99 and 0.97, respectively.
Conclusions: These results justify the usefulness of the designed high-frequency scanning system to determine the FMD and SR in the radial artery as predictors of coronary arterial disease. |
| format | Article |
| id | doaj-art-8d10aead748243e68660039b899b87f0 |
| institution | Kabale University |
| issn | 0137-5075 2300-262X |
| language | English |
| publishDate | 2019-07-01 |
| publisher | Institute of Fundamental Technological Research Polish Academy of Sciences |
| record_format | Article |
| series | Archives of Acoustics |
| spelling | doaj-art-8d10aead748243e68660039b899b87f02025-08-20T03:33:53ZengInstitute of Fundamental Technological Research Polish Academy of SciencesArchives of Acoustics0137-50752300-262X2019-07-0144410.24425/aoa.2019.129276Assessment of High Frequency Imaging and Doppler System for the Measurements of the Radial Artery Flow-Mediated DilationAndrzej NOWICKI0Barbara GAMBIN1Wojciech SECOMSKI2Zbigniew TRAWŃSKI3Michał SZUBIELSKI4Ryszard TYMKIEWICZ5Robert OLSZEWSKI6Institute of the Fundamental Technological Research, Polish Academy of SciencesInstitute of the Fundamental Technological Research, Polish Academy of SciencesInstitute of the Fundamental Technological Research, Polish Academy of SciencesInstitute of the Fundamental Technological Research, Polish Academy of SciencesMazovia Regional Hospital in SiedlceInstitute of the Fundamental Technological Research, Polish Academy of Sciences1) Department of Gerontology, Public Health and Didactics, National Institute of Geriatrics, Rheumatology and Rehabilitation 2) Institute of the Fundamental Technological Research, Polish Academy of SciencesObjectives: In the article we describe the new, high frequency, 20 MHz scanning/Doppler probe designed to measure the flow mediated dilation (FMD) and shear rate (SR) close to the radial artery wall. Methods: We compare two US scanning systems, standard vascular modality working below 12 MHz and high frequency 20 MHz system designed for FMD and SR measurements. Axial resolutions of both systems were compared by imaging of two closely spaced food plastic foils immersed in water and by measuring systolic/diastolic diameter changes in the radial artery. The sensitivities of Doppler modalities were also determined. The diagnostic potential of a high frequency system in measurements of FMD and SR was studied in vivo, in two groups of subjects, 12 healthy volunteers and 14 patients with stable coronary artery disease (CAD). Results: Over three times better axial resolution was demonstrated for a high frequency system. Also, the sensitivity of the external single transducer 20 MHz pulse Doppler proved to be over 20 dB better (in terms of a signal-to-noise ratio) than the pulse Doppler incorporated into the linear array. Statistically significant differences in FMD and FMD/SR values for healthy volunteers and CAD patients were confirmed, p-values < 0:05. The areas under Receiver Operating Characteristic (ROC) curves for FMD and FMD/SR for the prediction CAD had the values of 0.99 and 0.97, respectively. Conclusions: These results justify the usefulness of the designed high-frequency scanning system to determine the FMD and SR in the radial artery as predictors of coronary arterial disease.https://acoustics.ippt.pan.pl/index.php/aa/article/view/2590flow mediated dilationshear rateaxial resolutionelevation resolutionpulsed Dopplerultrasonic imaging |
| spellingShingle | Andrzej NOWICKI Barbara GAMBIN Wojciech SECOMSKI Zbigniew TRAWŃSKI Michał SZUBIELSKI Ryszard TYMKIEWICZ Robert OLSZEWSKI Assessment of High Frequency Imaging and Doppler System for the Measurements of the Radial Artery Flow-Mediated Dilation Archives of Acoustics flow mediated dilation shear rate axial resolution elevation resolution pulsed Doppler ultrasonic imaging |
| title | Assessment of High Frequency Imaging and Doppler System for the Measurements of the Radial Artery Flow-Mediated Dilation |
| title_full | Assessment of High Frequency Imaging and Doppler System for the Measurements of the Radial Artery Flow-Mediated Dilation |
| title_fullStr | Assessment of High Frequency Imaging and Doppler System for the Measurements of the Radial Artery Flow-Mediated Dilation |
| title_full_unstemmed | Assessment of High Frequency Imaging and Doppler System for the Measurements of the Radial Artery Flow-Mediated Dilation |
| title_short | Assessment of High Frequency Imaging and Doppler System for the Measurements of the Radial Artery Flow-Mediated Dilation |
| title_sort | assessment of high frequency imaging and doppler system for the measurements of the radial artery flow mediated dilation |
| topic | flow mediated dilation shear rate axial resolution elevation resolution pulsed Doppler ultrasonic imaging |
| url | https://acoustics.ippt.pan.pl/index.php/aa/article/view/2590 |
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