Fully integrated wearable control system for micro/nanorobot navigation

Micro/nanorobots have exhibited excellent application potential in the biomedical field, such as drug delivery, minimally invasive surgery, and bio-sensing. Furthermore, in order to achieve practical application, it is essential for swimming micro/nanorobots to navigate towards specific targets or a...

Full description

Saved in:
Bibliographic Details
Main Authors: Zhanxiang Zhang, Lin Wang, Fengqi Jiang, Shimin Yu, Fengtong Ji, Tianhao Sun, He Zhang, Yanhe Zhu, Hao Chang, Tianlong Li, Jie Zhao
Format: Article
Language:English
Published: IOP Publishing 2025-01-01
Series:International Journal of Extreme Manufacturing
Subjects:
Online Access:https://doi.org/10.1088/2631-7990/ada8e5
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1823860508649848832
author Zhanxiang Zhang
Lin Wang
Fengqi Jiang
Shimin Yu
Fengtong Ji
Tianhao Sun
He Zhang
Yanhe Zhu
Hao Chang
Tianlong Li
Jie Zhao
author_facet Zhanxiang Zhang
Lin Wang
Fengqi Jiang
Shimin Yu
Fengtong Ji
Tianhao Sun
He Zhang
Yanhe Zhu
Hao Chang
Tianlong Li
Jie Zhao
author_sort Zhanxiang Zhang
collection DOAJ
description Micro/nanorobots have exhibited excellent application potential in the biomedical field, such as drug delivery, minimally invasive surgery, and bio-sensing. Furthermore, in order to achieve practical application, it is essential for swimming micro/nanorobots to navigate towards specific targets or adjust their speed and morphology in complete environments. The navigation of swimming micro/nanorobots with temporal and spatial precision is critical for fulfilling the demand of applications. Here, we introduced a fully integrated wearable control system for micro/nanorobots navigation and manipulation, which is composed of a multifunctional sensor array, an artificial intelligence (AI) planner, and a magnetic field generator. The sensor array could perceive real-time changes in gestures, wrist rotation, and acoustic signals. AI planner based on machine learning offers adaptive path planning in response to dynamically changing signals to generate magnetic fields for the on-demand manipulation of micro/nanorobots. Such a novel, feasible control strategy was validated in the biological experiment in which cancer cells were targeted and killed by photothermal therapy using micro/nanorobots and integrated control platform. This wearable control system could play a crucial role in future intelligent medical applications and could be easily reconfigured toward other medical robots’ control.
format Article
id doaj-art-8d0dc2a730a747f491b410e8bcf38fad
institution Kabale University
issn 2631-7990
language English
publishDate 2025-01-01
publisher IOP Publishing
record_format Article
series International Journal of Extreme Manufacturing
spelling doaj-art-8d0dc2a730a747f491b410e8bcf38fad2025-02-10T12:56:08ZengIOP PublishingInternational Journal of Extreme Manufacturing2631-79902025-01-017303550510.1088/2631-7990/ada8e5Fully integrated wearable control system for micro/nanorobot navigationZhanxiang Zhang0Lin Wang1Fengqi Jiang2Shimin Yu3Fengtong Ji4https://orcid.org/0000-0002-9624-3503Tianhao Sun5He Zhang6Yanhe Zhu7Hao Chang8Tianlong Li9https://orcid.org/0000-0002-9483-457XJie Zhao10State Key Laboratory of Robotics and System Harbin Institute of Technology , Harbin 150001, People’s Republic of ChinaState Key Laboratory of Robotics and System Harbin Institute of Technology , Harbin 150001, People’s Republic of China; Harbin Institute of Technology Suzhou Research Institute , Suzhou 215104, People’s Republic of ChinaDepartment of General Surgery, Heilongjiang Provincial Hospital , Harbin 150001, People’s Republic of ChinaCollege of Engineering, Ocean University of China , Qingdao 266100, People’s Republic of ChinaGurdon Institute, University of Cambridge , Cambridge, CB2 1QN, United Kingdom; Department of Physiology, Development and Neuroscience, University of Cambridge , Cambridge CB2 3DY, United KingdomDepartment of Thoracic Surgery, The First Affiliated Hospital of Harbin Medical University , Harbin 150001, People’s Republic of ChinaState Key Laboratory of Robotics and System Harbin Institute of Technology , Harbin 150001, People’s Republic of ChinaState Key Laboratory of Robotics and System Harbin Institute of Technology , Harbin 150001, People’s Republic of ChinaDepartment of Thoracic Surgery, The First Affiliated Hospital of Harbin Medical University , Harbin 150001, People’s Republic of ChinaState Key Laboratory of Robotics and System Harbin Institute of Technology , Harbin 150001, People’s Republic of China; Harbin Institute of Technology Suzhou Research Institute , Suzhou 215104, People’s Republic of ChinaState Key Laboratory of Robotics and System Harbin Institute of Technology , Harbin 150001, People’s Republic of ChinaMicro/nanorobots have exhibited excellent application potential in the biomedical field, such as drug delivery, minimally invasive surgery, and bio-sensing. Furthermore, in order to achieve practical application, it is essential for swimming micro/nanorobots to navigate towards specific targets or adjust their speed and morphology in complete environments. The navigation of swimming micro/nanorobots with temporal and spatial precision is critical for fulfilling the demand of applications. Here, we introduced a fully integrated wearable control system for micro/nanorobots navigation and manipulation, which is composed of a multifunctional sensor array, an artificial intelligence (AI) planner, and a magnetic field generator. The sensor array could perceive real-time changes in gestures, wrist rotation, and acoustic signals. AI planner based on machine learning offers adaptive path planning in response to dynamically changing signals to generate magnetic fields for the on-demand manipulation of micro/nanorobots. Such a novel, feasible control strategy was validated in the biological experiment in which cancer cells were targeted and killed by photothermal therapy using micro/nanorobots and integrated control platform. This wearable control system could play a crucial role in future intelligent medical applications and could be easily reconfigured toward other medical robots’ control.https://doi.org/10.1088/2631-7990/ada8e5micro/nanorobotwearable control systemmachine learningtargeted delivery
spellingShingle Zhanxiang Zhang
Lin Wang
Fengqi Jiang
Shimin Yu
Fengtong Ji
Tianhao Sun
He Zhang
Yanhe Zhu
Hao Chang
Tianlong Li
Jie Zhao
Fully integrated wearable control system for micro/nanorobot navigation
International Journal of Extreme Manufacturing
micro/nanorobot
wearable control system
machine learning
targeted delivery
title Fully integrated wearable control system for micro/nanorobot navigation
title_full Fully integrated wearable control system for micro/nanorobot navigation
title_fullStr Fully integrated wearable control system for micro/nanorobot navigation
title_full_unstemmed Fully integrated wearable control system for micro/nanorobot navigation
title_short Fully integrated wearable control system for micro/nanorobot navigation
title_sort fully integrated wearable control system for micro nanorobot navigation
topic micro/nanorobot
wearable control system
machine learning
targeted delivery
url https://doi.org/10.1088/2631-7990/ada8e5
work_keys_str_mv AT zhanxiangzhang fullyintegratedwearablecontrolsystemformicronanorobotnavigation
AT linwang fullyintegratedwearablecontrolsystemformicronanorobotnavigation
AT fengqijiang fullyintegratedwearablecontrolsystemformicronanorobotnavigation
AT shiminyu fullyintegratedwearablecontrolsystemformicronanorobotnavigation
AT fengtongji fullyintegratedwearablecontrolsystemformicronanorobotnavigation
AT tianhaosun fullyintegratedwearablecontrolsystemformicronanorobotnavigation
AT hezhang fullyintegratedwearablecontrolsystemformicronanorobotnavigation
AT yanhezhu fullyintegratedwearablecontrolsystemformicronanorobotnavigation
AT haochang fullyintegratedwearablecontrolsystemformicronanorobotnavigation
AT tianlongli fullyintegratedwearablecontrolsystemformicronanorobotnavigation
AT jiezhao fullyintegratedwearablecontrolsystemformicronanorobotnavigation