Precise prediction of bone metastases and metastatic burden using exosomal mirnas and radiomics: a multi-center study

Precise prediction of bone metastases and metastatic burden using exosomal mirnas and radiomics: a multi-center study

Abstract Background Bone metastasis of prostate cancer (PCa) is a challenging problem, leading to poor prognosis of patients. Existing biomarkers have limited sensitivity and specificity. Therefore, we urgently need a novel diagnostic tool to predict PCa bone metastasis. Methods Patient data and blo...

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Bibliographic Details
Main Authors: Chao Wang, Xu-Pan Wei, Chuan Zhou, Jia Wang, Yun-Feng Zhang, Han He, Wen-Bo Zhang, Hao-Xuan Lv, Fang Wang, Feng-Hai Zhou
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Journal of Translational Medicine
Subjects:
PCa
miRNAs
Radiomics
Exosomes
Biomarkers
Online Access:https://doi.org/10.1186/s12967-025-06691-0
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