The role of hypoxia-senescence co-related molecular subtypes and prognostic characteristics in hepatocellular carcinoma

The role of hypoxia-senescence co-related molecular subtypes and prognostic characteristics in hepatocellular carcinoma

Abstract Hepatocellular carcinoma (HCC) is known for its high invasiveness, high fatality rate. Both hypoxia and senescence play crucial roles in the initiation and progression of cancer, yet their prognostic implications in HCC are yet to be fully understood. The hypoxia-senescence co-related genes...

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Bibliographic Details
Main Authors: Fuqing Chen, Yifan Cai, Xiangmei Chen, Changzhou Chen, Qinliang Fang, Jianming Liu, Yibin Zhang, Jianyin Zhou
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Scientific Reports
Subjects:
Hepatocellular carcinoma
Hypoxia
Senescence
Molecular subtypes
Prognostic risk model
MLH1
Online Access:https://doi.org/10.1038/s41598-025-97604-0
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