Study of anti-Toxoplasma gondii effect of mPEG–PCL copolymeric loaded with pyrimethamine, in vitro

Study of anti-Toxoplasma gondii effect of mPEG–PCL copolymeric loaded with pyrimethamine, in vitro

Abstract The discovery of new drugs with minimal toxicity is crucially important in the search for effective treatments for toxoplasmosis. The study aimed to assess the effectiveness of pyrimethamine-loaded mPEG–PCL copolymeric nanoparticles (mPEG–PCL–Pyr) against Toxoplasma gondii (T. gondii) tachy...

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Bibliographic Details
Main Authors: Mobina Gholami, Hossein Danafer, Mitra Sadeghi, Ahmad Daryani, Seyed Abdollah Hosseini, Shirzad Gholami
Format: Article
Language:English
Published: SpringerOpen 2025-05-01
Series:AMB Express
Subjects:
Antiparasitic effect
mPEG–PCL copolymer nanoparticles
Pyrimethamine
Toxoplasma gondii
In vitro
Online Access:https://doi.org/10.1186/s13568-025-01876-8
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