Cost-effectiveness of support for health professionals to implement physical activity promotion: a protocol for within-trial and modelled economic evaluations of the PROMOTE-PA effectiveness-implementation hybrid trial
Introduction Physical activity has important benefits for the prevention and management of chronic diseases and healthy ageing. Health professionals have valuable opportunities to promote physical activity to a large group of people across the lifespan. Promotion of Physical Activity by Health Profe...
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BMJ Publishing Group
2025-04-01
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| Series: | BMJ Open |
| Online Access: | https://bmjopen.bmj.com/content/15/4/e098452.full |
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| author | Kirsten Howard Anne Tiedemann Catherine Sherrington Michael Noetel Marina Pinheiro Leanne Hassett Sakina Chagpar Belinda Wang Georgina Clutterbuck Jennifer N Baldwin Daniel Cheung Kate Purcell Roslyn Savage |
| author_facet | Kirsten Howard Anne Tiedemann Catherine Sherrington Michael Noetel Marina Pinheiro Leanne Hassett Sakina Chagpar Belinda Wang Georgina Clutterbuck Jennifer N Baldwin Daniel Cheung Kate Purcell Roslyn Savage |
| author_sort | Kirsten Howard |
| collection | DOAJ |
| description | Introduction Physical activity has important benefits for the prevention and management of chronic diseases and healthy ageing. Health professionals have valuable opportunities to promote physical activity to a large group of people across the lifespan. Promotion of Physical Activity by Health Professionals is a hybrid type 1 effectiveness-implementation cluster randomised trial designed to evaluate the impact of physical activity promotion by health professionals (n=30 clusters) on physical activity participation in their patients (n=720). To inform the future implementation of this programme, we will be conducting a within-trial and modelled economic evaluation.Methods and analysis We will conduct a cost-effectiveness and cost-utility analysis from the perspective of the healthcare, aged care and disability funder. The time horizon will be 6 months for the within-trial analysis and 2 years for the modelled analysis. Data on intervention costs will be collected using trial records. Data on healthcare utilisation will be collected using data linkage. Incremental cost-effectiveness ratios (ICERs) will be reported for physical activity and quality-adjusted life years outcomes. Bootstrapping will be used to explore uncertainty around the ICERs and estimate 95% CIs. Results will be presented on a cost-effectiveness plane. The probability that the intervention would be cost-effective at varying willingness-to-pay thresholds will be presented using a cost-effectiveness acceptability curve.Ethics and dissemination Ethics approval was obtained through Sydney Local Health District (RPAH zone) Ethics Review Committee (X23-0197). The findings of this study will be disseminated through peer-reviewed journal articles and conference presentations.Trial registration number Australian New Zealand Clinical Trials Registry: ACTRN12623000920695. |
| format | Article |
| id | doaj-art-8cfcd07a36944c1d853a8139eee37a88 |
| institution | OA Journals |
| issn | 2044-6055 |
| language | English |
| publishDate | 2025-04-01 |
| publisher | BMJ Publishing Group |
| record_format | Article |
| series | BMJ Open |
| spelling | doaj-art-8cfcd07a36944c1d853a8139eee37a882025-08-20T02:25:36ZengBMJ Publishing GroupBMJ Open2044-60552025-04-0115410.1136/bmjopen-2024-098452Cost-effectiveness of support for health professionals to implement physical activity promotion: a protocol for within-trial and modelled economic evaluations of the PROMOTE-PA effectiveness-implementation hybrid trialKirsten Howard0Anne Tiedemann1Catherine Sherrington2Michael Noetel3Marina Pinheiro4Leanne Hassett5Sakina Chagpar6Belinda Wang7Georgina Clutterbuck8Jennifer N Baldwin9Daniel Cheung10Kate Purcell11Roslyn Savage12The Leeder Centre for Health Policy, Economics and Data, The University of Sydney, Sydney, New South Wales, AustraliaSchool of Public Health, Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, AustraliaSchool of Public Health, Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, AustraliaSchool of Psychology, The University of Queensland, Brisbane, Queensland, AustraliaSchool of Public Health, Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, AustraliaInstitute for Musculoskeletal Health, Sydney Local Health District, Sydney, New South Wales, AustraliaSchool of Public Health, Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, AustraliaSchool of Public Health, Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, AustraliaSchool of Health and Rehabilitation Sciences, The University of Queensland, Brisbane, Queensland, AustraliaSchool of Public Health, Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, AustraliaInstitute for Musculoskeletal Health, Sydney Local Health District, Sydney, New South Wales, AustraliaSchool of Public Health, Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, AustraliaSchool of Public Health, Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, AustraliaIntroduction Physical activity has important benefits for the prevention and management of chronic diseases and healthy ageing. Health professionals have valuable opportunities to promote physical activity to a large group of people across the lifespan. Promotion of Physical Activity by Health Professionals is a hybrid type 1 effectiveness-implementation cluster randomised trial designed to evaluate the impact of physical activity promotion by health professionals (n=30 clusters) on physical activity participation in their patients (n=720). To inform the future implementation of this programme, we will be conducting a within-trial and modelled economic evaluation.Methods and analysis We will conduct a cost-effectiveness and cost-utility analysis from the perspective of the healthcare, aged care and disability funder. The time horizon will be 6 months for the within-trial analysis and 2 years for the modelled analysis. Data on intervention costs will be collected using trial records. Data on healthcare utilisation will be collected using data linkage. Incremental cost-effectiveness ratios (ICERs) will be reported for physical activity and quality-adjusted life years outcomes. Bootstrapping will be used to explore uncertainty around the ICERs and estimate 95% CIs. Results will be presented on a cost-effectiveness plane. The probability that the intervention would be cost-effective at varying willingness-to-pay thresholds will be presented using a cost-effectiveness acceptability curve.Ethics and dissemination Ethics approval was obtained through Sydney Local Health District (RPAH zone) Ethics Review Committee (X23-0197). The findings of this study will be disseminated through peer-reviewed journal articles and conference presentations.Trial registration number Australian New Zealand Clinical Trials Registry: ACTRN12623000920695.https://bmjopen.bmj.com/content/15/4/e098452.full |
| spellingShingle | Kirsten Howard Anne Tiedemann Catherine Sherrington Michael Noetel Marina Pinheiro Leanne Hassett Sakina Chagpar Belinda Wang Georgina Clutterbuck Jennifer N Baldwin Daniel Cheung Kate Purcell Roslyn Savage Cost-effectiveness of support for health professionals to implement physical activity promotion: a protocol for within-trial and modelled economic evaluations of the PROMOTE-PA effectiveness-implementation hybrid trial BMJ Open |
| title | Cost-effectiveness of support for health professionals to implement physical activity promotion: a protocol for within-trial and modelled economic evaluations of the PROMOTE-PA effectiveness-implementation hybrid trial |
| title_full | Cost-effectiveness of support for health professionals to implement physical activity promotion: a protocol for within-trial and modelled economic evaluations of the PROMOTE-PA effectiveness-implementation hybrid trial |
| title_fullStr | Cost-effectiveness of support for health professionals to implement physical activity promotion: a protocol for within-trial and modelled economic evaluations of the PROMOTE-PA effectiveness-implementation hybrid trial |
| title_full_unstemmed | Cost-effectiveness of support for health professionals to implement physical activity promotion: a protocol for within-trial and modelled economic evaluations of the PROMOTE-PA effectiveness-implementation hybrid trial |
| title_short | Cost-effectiveness of support for health professionals to implement physical activity promotion: a protocol for within-trial and modelled economic evaluations of the PROMOTE-PA effectiveness-implementation hybrid trial |
| title_sort | cost effectiveness of support for health professionals to implement physical activity promotion a protocol for within trial and modelled economic evaluations of the promote pa effectiveness implementation hybrid trial |
| url | https://bmjopen.bmj.com/content/15/4/e098452.full |
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