A Novel Extended-Release Analgesic Without Periarticular Injection Provides Inferior Immediate Postsurgical Pain Relief in Total Hip and Knee Arthroplasty Patients

A Novel Extended-Release Analgesic Without Periarticular Injection Provides Inferior Immediate Postsurgical Pain Relief in Total Hip and Knee Arthroplasty Patients

Background: We compared early postoperative pain levels and rescue opioids between conventional bupivacaine-based periarticular injections (PAIs), a new extended-release (ER) solution comprised of bupivacaine and meloxicam, and a combination of both. Methods: A 40-week retrospective review was condu...

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Bibliographic Details
Main Authors: Catelyn A. Woelfle, BA, Klara Aastroem, BS, Roshan P. Shah, MD, Alexander L. Neuwirth, MD, H. John Cooper, MD
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Arthroplasty Today
Subjects:
Extended release bupivacaine
Periarticular injection
Total hip arthroplasty (THA)
Total knee arthroplasty (TKA)
Postoperative pain
Analgesia
Online Access:http://www.sciencedirect.com/science/article/pii/S2352344125000913
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