Advanced HIV as a Neglected Disease

Although HIV treatment coverage has increased substantially in recent years, the associated reductions in AIDS-related deaths have been smaller and slower than expected. The proportion of people with advanced HIV disease remains high: it is estimated that more than 4 million people have advanced HIV...

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Main Author: Joe Jarvis
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:International Journal of Infectious Diseases
Online Access:http://www.sciencedirect.com/science/article/pii/S1201971224004545
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author Joe Jarvis
author_facet Joe Jarvis
author_sort Joe Jarvis
collection DOAJ
description Although HIV treatment coverage has increased substantially in recent years, the associated reductions in AIDS-related deaths have been smaller and slower than expected. The proportion of people with advanced HIV disease remains high: it is estimated that more than 4 million people have advanced HIV disease, and each year more than 600,000 of them are expected to die. Many of these deaths can be prevented. Until recently, advanced HIV was viewed as a problem of late presentation, so the solution was thought to be testing more people and diagnosing the disease earlier. Although late presentation remains problematic, however, advanced HIV is now predominantly seen among people who started care but were not effectively engaged or have disengaged, returning only when they're ill. This talk will discuss who is at risk for the worst outcomes; which infections lead to the greatest morbidity and mortality; new tools for diagnosing, preventing, and treating these conditions; and how systems could adapt to delivering these tools effectively.
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spelling doaj-art-8ce2bb69956344718e00dff67201b8762025-08-20T02:11:00ZengElsevierInternational Journal of Infectious Diseases1201-97122025-03-0115210737910.1016/j.ijid.2024.107379Advanced HIV as a Neglected DiseaseJoe Jarvis0London School of Hygiene and Tropical Medicine, UKAlthough HIV treatment coverage has increased substantially in recent years, the associated reductions in AIDS-related deaths have been smaller and slower than expected. The proportion of people with advanced HIV disease remains high: it is estimated that more than 4 million people have advanced HIV disease, and each year more than 600,000 of them are expected to die. Many of these deaths can be prevented. Until recently, advanced HIV was viewed as a problem of late presentation, so the solution was thought to be testing more people and diagnosing the disease earlier. Although late presentation remains problematic, however, advanced HIV is now predominantly seen among people who started care but were not effectively engaged or have disengaged, returning only when they're ill. This talk will discuss who is at risk for the worst outcomes; which infections lead to the greatest morbidity and mortality; new tools for diagnosing, preventing, and treating these conditions; and how systems could adapt to delivering these tools effectively.http://www.sciencedirect.com/science/article/pii/S1201971224004545
spellingShingle Joe Jarvis
Advanced HIV as a Neglected Disease
International Journal of Infectious Diseases
title Advanced HIV as a Neglected Disease
title_full Advanced HIV as a Neglected Disease
title_fullStr Advanced HIV as a Neglected Disease
title_full_unstemmed Advanced HIV as a Neglected Disease
title_short Advanced HIV as a Neglected Disease
title_sort advanced hiv as a neglected disease
url http://www.sciencedirect.com/science/article/pii/S1201971224004545
work_keys_str_mv AT joejarvis advancedhivasaneglecteddisease