ATF7IP/SETDB1-mediated epigenetic programming regulates thymic homing and T lymphopoiesis of hematopoietic progenitors during embryogenesis
Abstract T lymphocytes, which are essential for cell-mediated immunity in vertebrates, rely on thymic seeding of lymphoid progenitors for commitment, differentiation and maturation. However, the epigenetic programming of lymphoid-primed progenitor migration and differentiation is incompletely unders...
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| Main Authors: | Wenqi Chen, Jiaxin Wu, Peilu She, Juan Li, Yuying Lan, Xueli Hu, Yangguo Huangfu, Chen Wu, Daqing Jin, Peng Xie, Guanglei Zhuang, Yuxuan Wu, Yiyue Zhang, Leonard I. Zon, Ping Zhu, Tao P. Zhong |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-07-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-025-61680-7 |
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