Identification of Shared Pathways and Molecules Between Type 2 Diabetes and Lung Adenocarcinoma and the Impact of High Glucose Environment on Lung Adenocarcinoma

Conclusion: The research established a shared pathogenic basis between LUAD and T2DM. TGF-β, HIF-1, AGE–RAGE, ECM components and function regulation, cell adhesion, and additional signaling pathways are intricately linked with the pathophysiological mechanisms underlying both LUAD and T2DM. Thus, ST...

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Bibliographic Details
Main Authors: Mengsi Yang, Jianmin Luo, Yunna Zheng, Qunqing Chen
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:International Journal of Endocrinology
Online Access:http://dx.doi.org/10.1155/ije/7734237
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