Inhibition of ATM enhances the immunogenicity of triple-negative breast cancer by promoting MHC-I expression
Abstract The immunotherapy has achieved some efficacy in triple-negative breast cancer (TNBC), but the benefit population is limited, primarily due to an abnormal immune microenvironment. Thus, it is necessary to explore new molecular targets to enhance the immunogenicity of TNBC cells and improve t...
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| Main Authors: | Jiazhen Li, Chenying Liu, Xiaolong Qian, Xiaozi Wang, Hui Sun, Lu Wang, Huiqin Xue, Yuanming Song, Jiamei Liu, Yafang Zhao, Yumian Jia, Fengxia Qin, Tianhua Zhang, Xiaojing Guo |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2025-08-01
|
| Series: | Cell Death and Disease |
| Online Access: | https://doi.org/10.1038/s41419-025-07944-y |
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