Topologically associating domains of chromatin on single-cell Hi-C data: a survey of bioinformatic tools and applications in the light of artificial intelligence

Topologically associating domains of chromatin on single-cell Hi-C data: a survey of bioinformatic tools and applications in the light of artificial intelligence

Topologically associating domains (TADs) uncovered on bulk Hi-C data are regarded as fundamental building blocks of a three-dimensional genome, and they are believed to effectively participate in the regulatory programs of gene expression. The computational analysis of TADs on single-cell Hi-C (scHi...

Full description

Saved in:
Bibliographic Details
Main Authors: Hongqiang Lyu, Yao Li, Xinran Chen, Yuan Liu, Erhu Liu, Xiaoliang Cheng
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Genetics
Subjects:
topologically associating domains
single-cell Hi-C
bioinformatics tools and applications
artificial intelligence
challenges and emerging trends
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2025.1602234/full
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items