Computational Drug Repositioning of Mast Cell Stabilizers against Human Protease-Activated Receptor 2 (PAR2) Involved in Rheumatoid Arthritis

Protease-activated receptor 2 (PAR2) plays a pivotal role in activating pain and inflammation pathways in rheumatoid arthritis (RA), contributing to cartilage destruction, synovial inflammation, and heightened joint pain [...]

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Bibliographic Details
Main Authors: Khushboo Choudhury, Ram Singh Purty, Kanika Khoba
Format: Article
Language:English
Published: MDPI AG 2024-04-01
Series:Proceedings
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Online Access:https://www.mdpi.com/2504-3900/103/1/75
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Summary:Protease-activated receptor 2 (PAR2) plays a pivotal role in activating pain and inflammation pathways in rheumatoid arthritis (RA), contributing to cartilage destruction, synovial inflammation, and heightened joint pain [...]
ISSN:2504-3900