Suspected Transfusion Related Acute Lung Injury Improving following Administration of Tranexamic Acid: A Case Report
A 16-year-old woman with craniofacial injury developed severe acute respiratory failure under the primary reconstructive surgical procedure requiring several units of blood and plasma. A transfusion related acute lung injury (TRALI) was suspected and supportive treatment was initiated. Because of th...
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| Format: | Article |
| Language: | English |
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Wiley
2014-01-01
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| Series: | Case Reports in Anesthesiology |
| Online Access: | http://dx.doi.org/10.1155/2014/710813 |
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| author | Stan Ryniak Piotr Harbut Anders Östlund Andrzej Mysiak Jan G. Jakobsson |
| author_facet | Stan Ryniak Piotr Harbut Anders Östlund Andrzej Mysiak Jan G. Jakobsson |
| author_sort | Stan Ryniak |
| collection | DOAJ |
| description | A 16-year-old woman with craniofacial injury developed severe acute respiratory failure under the primary reconstructive surgical procedure requiring several units of blood and plasma. A transfusion related acute lung injury (TRALI) was suspected and supportive treatment was initiated. Because of the severity of symptoms, acute extracorporeal membrane oxygenation (ECMO) was planned. During preparation for ECMO, a single intravenous dose, 1 g of tranexamic acid, was administered and a remarkable improvement was observed shortly thereafter. The patient was placed on ECMO for 16 hours. The further course was uncomplicated and the patient was discharged from ICU on the 6th day after admission fully and she recovered. A clinical improvement was observed in a timely fashion following the administration of tranexamic acid. The handling of a suspected TRALI and potential benefit from administration of tranexamic acid are discussed in this case report. |
| format | Article |
| id | doaj-art-8cc10f405ce149efab6d42a834b5bbaf |
| institution | OA Journals |
| issn | 2090-6382 2090-6390 |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Anesthesiology |
| spelling | doaj-art-8cc10f405ce149efab6d42a834b5bbaf2025-08-20T02:09:34ZengWileyCase Reports in Anesthesiology2090-63822090-63902014-01-01201410.1155/2014/710813710813Suspected Transfusion Related Acute Lung Injury Improving following Administration of Tranexamic Acid: A Case ReportStan Ryniak0Piotr Harbut1Anders Östlund2Andrzej Mysiak3Jan G. Jakobsson4Department of Anaesthesia & Intensive Care, Karolinska Institutet, Danderyds University Hospital, Danderyd, 182 88 Stockholm, SwedenDepartment of Anaesthesia & Intensive Care, Karolinska Institutet, Danderyds University Hospital, Danderyd, 182 88 Stockholm, SwedenSection for Trauma and Acute Anaesthesiology, Karolinska Institutet, Karolinska University Hospital, Danderyd, 182 88 Stockholm, SwedenDepartment of Cardiology, Medical University, 50-367 Wroclaw, PolandDepartment of Anaesthesia & Intensive Care, Karolinska Institutet, Danderyds University Hospital, Danderyd, 182 88 Stockholm, SwedenA 16-year-old woman with craniofacial injury developed severe acute respiratory failure under the primary reconstructive surgical procedure requiring several units of blood and plasma. A transfusion related acute lung injury (TRALI) was suspected and supportive treatment was initiated. Because of the severity of symptoms, acute extracorporeal membrane oxygenation (ECMO) was planned. During preparation for ECMO, a single intravenous dose, 1 g of tranexamic acid, was administered and a remarkable improvement was observed shortly thereafter. The patient was placed on ECMO for 16 hours. The further course was uncomplicated and the patient was discharged from ICU on the 6th day after admission fully and she recovered. A clinical improvement was observed in a timely fashion following the administration of tranexamic acid. The handling of a suspected TRALI and potential benefit from administration of tranexamic acid are discussed in this case report.http://dx.doi.org/10.1155/2014/710813 |
| spellingShingle | Stan Ryniak Piotr Harbut Anders Östlund Andrzej Mysiak Jan G. Jakobsson Suspected Transfusion Related Acute Lung Injury Improving following Administration of Tranexamic Acid: A Case Report Case Reports in Anesthesiology |
| title | Suspected Transfusion Related Acute Lung Injury Improving following Administration of Tranexamic Acid: A Case Report |
| title_full | Suspected Transfusion Related Acute Lung Injury Improving following Administration of Tranexamic Acid: A Case Report |
| title_fullStr | Suspected Transfusion Related Acute Lung Injury Improving following Administration of Tranexamic Acid: A Case Report |
| title_full_unstemmed | Suspected Transfusion Related Acute Lung Injury Improving following Administration of Tranexamic Acid: A Case Report |
| title_short | Suspected Transfusion Related Acute Lung Injury Improving following Administration of Tranexamic Acid: A Case Report |
| title_sort | suspected transfusion related acute lung injury improving following administration of tranexamic acid a case report |
| url | http://dx.doi.org/10.1155/2014/710813 |
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