Acute Hemorrhagic Edema of Infancy after Coronavirus Infection with Recurrent Rash

Purpura, particularly when accompanied by fever, is a worrisome finding in children. Acute hemorrhagic edema of infancy (AHEI) is a benign type of small-vessel leukocytoclastic vasculitis that presents with progressive purpura and has an excellent prognosis. Patients with AHEI present with large, ta...

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Main Authors: Hannah Chesser, Jeffrey M. Chambliss, Eric Zwemer
Format: Article
Language:English
Published: Wiley 2017-01-01
Series:Case Reports in Pediatrics
Online Access:http://dx.doi.org/10.1155/2017/5637503
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author Hannah Chesser
Jeffrey M. Chambliss
Eric Zwemer
author_facet Hannah Chesser
Jeffrey M. Chambliss
Eric Zwemer
author_sort Hannah Chesser
collection DOAJ
description Purpura, particularly when accompanied by fever, is a worrisome finding in children. Acute hemorrhagic edema of infancy (AHEI) is a benign type of small-vessel leukocytoclastic vasculitis that presents with progressive purpura and has an excellent prognosis. Patients with AHEI present with large, target-like purpuric plaques affecting the face, ear lobes, and extremities. While the rapid onset of these skin findings can be dramatic, the child with AHEI is usually well appearing with reassuring laboratory testing. We describe a case of a previously healthy 8-month-old female who presented with progressive purpura in a nondependent distribution, low-grade fevers, and extremity swelling. An extensive workup was performed prior to making the diagnosis of AHEI. Coronavirus was implicated as the likely triggering pathogen, and the patient suffered a recurrence of purpuric rash and swelling several weeks after her initial presentation.
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spelling doaj-art-8cb9b87de79f404a8840b0f6bba8a7892025-08-20T02:09:35ZengWileyCase Reports in Pediatrics2090-68032090-68112017-01-01201710.1155/2017/56375035637503Acute Hemorrhagic Edema of Infancy after Coronavirus Infection with Recurrent RashHannah Chesser0Jeffrey M. Chambliss1Eric Zwemer2Department of Pediatrics, University of North Carolina, Chapel Hill, NC, USADepartment of Pediatrics, University of Texas Medical Branch, Galveston, TX, USADepartment of Pediatrics, University of North Carolina, Chapel Hill, NC, USAPurpura, particularly when accompanied by fever, is a worrisome finding in children. Acute hemorrhagic edema of infancy (AHEI) is a benign type of small-vessel leukocytoclastic vasculitis that presents with progressive purpura and has an excellent prognosis. Patients with AHEI present with large, target-like purpuric plaques affecting the face, ear lobes, and extremities. While the rapid onset of these skin findings can be dramatic, the child with AHEI is usually well appearing with reassuring laboratory testing. We describe a case of a previously healthy 8-month-old female who presented with progressive purpura in a nondependent distribution, low-grade fevers, and extremity swelling. An extensive workup was performed prior to making the diagnosis of AHEI. Coronavirus was implicated as the likely triggering pathogen, and the patient suffered a recurrence of purpuric rash and swelling several weeks after her initial presentation.http://dx.doi.org/10.1155/2017/5637503
spellingShingle Hannah Chesser
Jeffrey M. Chambliss
Eric Zwemer
Acute Hemorrhagic Edema of Infancy after Coronavirus Infection with Recurrent Rash
Case Reports in Pediatrics
title Acute Hemorrhagic Edema of Infancy after Coronavirus Infection with Recurrent Rash
title_full Acute Hemorrhagic Edema of Infancy after Coronavirus Infection with Recurrent Rash
title_fullStr Acute Hemorrhagic Edema of Infancy after Coronavirus Infection with Recurrent Rash
title_full_unstemmed Acute Hemorrhagic Edema of Infancy after Coronavirus Infection with Recurrent Rash
title_short Acute Hemorrhagic Edema of Infancy after Coronavirus Infection with Recurrent Rash
title_sort acute hemorrhagic edema of infancy after coronavirus infection with recurrent rash
url http://dx.doi.org/10.1155/2017/5637503
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