Virtual reality navigation for the early detection of Alzheimer’s disease

Virtual reality navigation for the early detection of Alzheimer’s disease

ObjectiveThe development of non-invasive clinical diagnostics is paramount for the early detection of Alzheimer’s disease (AD). Neurofibrillary tangles in AD originate from the entorhinal cortex, a cortical memory area that mediates navigation via path integration (PI). Here, we studied correlations...

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Bibliographic Details
Main Authors:	Sayuri Shima, Reiko Ohdake, Yasuaki Mizutani, Harutsugu Tatebe, Riki Koike, Atsushi Kasai, Epifanio Bagarinao, Kazuya Kawabata, Akihiro Ueda, Mizuki Ito, Junichi Hata, Shinsuke Ishigaki, Junichiro Yoshimoto, Hiroshi Toyama, Takahiko Tokuda, Akihiko Takashima, Hirohisa Watanabe
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-08-01
Series:	Frontiers in Aging Neuroscience
Subjects:	apolipoprotein E cognitive dysfunction entorhinal cortex glial fibrillary acidic protein magnetic resonance imaging spatial memory
Online Access:	https://www.frontiersin.org/articles/10.3389/fnagi.2025.1571429/full
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