Maternal risk factors for preterm birth in Taiwan, a nationwide population-based cohort study

Background: The rate of preterm birth is increasing globally. It causes significant short-term and long-term health care burdens. A comprehensive recognition of the risk factors related to preterm births is important in the prevention of preterm birth. Our study is to investigate the incidence and m...

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Main Authors: Sheng-Ting Wu, Ching-Heng Lin, Yi-Hsuan Lin, Ya-Chi Hsu, Chung-Ting Hsu, Ming-Chih Lin
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:Pediatrics and Neonatology
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Online Access:http://www.sciencedirect.com/science/article/pii/S1875957223001225
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author Sheng-Ting Wu
Ching-Heng Lin
Yi-Hsuan Lin
Ya-Chi Hsu
Chung-Ting Hsu
Ming-Chih Lin
author_facet Sheng-Ting Wu
Ching-Heng Lin
Yi-Hsuan Lin
Ya-Chi Hsu
Chung-Ting Hsu
Ming-Chih Lin
author_sort Sheng-Ting Wu
collection DOAJ
description Background: The rate of preterm birth is increasing globally. It causes significant short-term and long-term health care burdens. A comprehensive recognition of the risk factors related to preterm births is important in the prevention of preterm birth. Our study is to investigate the incidence and maternal risk factors of preterm birth from a nationwide population-based perspective. Methods: This is a retrospective cohort study. All live births from 2004 to 2014 in Taiwan enrolled. The main data source was Taiwan’s Birth Certificate Application (BCA) database. The BCA database was linked with the National Health Insurance Research Database (NHIRD) to establish any links between information on newborns and maternal underlying disease. Results: A total of 1,385,979 births were included in the analysis. The incidence of preterm birth increased gradually in Taiwan from 8.85% in 2004 to 10.73% in 2014. Maternal age, socioeconomic status, maternal allergy and autoimmune diseases, gynecological diseases, and pregnancy-related complications were significant risk factors for preterm birth. Conclusion: The overall incidence of preterm births has gradually increased in Taiwan. Maternal age, socioeconomic status, certain underlying diseases, and pregnancy-related complications were risk factors for preterm birth.
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spelling doaj-art-8ca4e3ce72594314ba5459ac6a94949f2025-08-20T02:09:35ZengElsevierPediatrics and Neonatology1875-95722024-01-01651384710.1016/j.pedneo.2023.03.014Maternal risk factors for preterm birth in Taiwan, a nationwide population-based cohort studySheng-Ting Wu0Ching-Heng Lin1Yi-Hsuan Lin2Ya-Chi Hsu3Chung-Ting Hsu4Ming-Chih Lin5Children's Medical Center, Taichung Veterans General Hospital, Taichung, TaiwanDepartment of Medical Research, Taichung Veterans General Hospital, Taichung, TaiwanChildren's Medical Center, Taichung Veterans General Hospital, Taichung, Taiwan; Department of Post-Baccalaureate Medicine, College of Medicine, National Chung Hsing University, Taichung, TaiwanChildren's Medical Center, Taichung Veterans General Hospital, Taichung, TaiwanChildren's Medical Center, Taichung Veterans General Hospital, Taichung, Taiwan; Department of Post-Baccalaureate Medicine, College of Medicine, National Chung Hsing University, Taichung, TaiwanChildren's Medical Center, Taichung Veterans General Hospital, Taichung, Taiwan; Department of Post-Baccalaureate Medicine, College of Medicine, National Chung Hsing University, Taichung, Taiwan; School of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan; Department of Food and Nutrition, Providence University, Taichung, Taiwan; School of Medicine, Chung Shan Medical University, Taichung, Taiwan; Corresponding author. 1650 Taiwan Boulevard Sec. 4, Taichung 40705. Taiwan.Background: The rate of preterm birth is increasing globally. It causes significant short-term and long-term health care burdens. A comprehensive recognition of the risk factors related to preterm births is important in the prevention of preterm birth. Our study is to investigate the incidence and maternal risk factors of preterm birth from a nationwide population-based perspective. Methods: This is a retrospective cohort study. All live births from 2004 to 2014 in Taiwan enrolled. The main data source was Taiwan’s Birth Certificate Application (BCA) database. The BCA database was linked with the National Health Insurance Research Database (NHIRD) to establish any links between information on newborns and maternal underlying disease. Results: A total of 1,385,979 births were included in the analysis. The incidence of preterm birth increased gradually in Taiwan from 8.85% in 2004 to 10.73% in 2014. Maternal age, socioeconomic status, maternal allergy and autoimmune diseases, gynecological diseases, and pregnancy-related complications were significant risk factors for preterm birth. Conclusion: The overall incidence of preterm births has gradually increased in Taiwan. Maternal age, socioeconomic status, certain underlying diseases, and pregnancy-related complications were risk factors for preterm birth.http://www.sciencedirect.com/science/article/pii/S1875957223001225premature birthmaternal healthpregnancyhigh-riskpregnancy complicationsperinatology
spellingShingle Sheng-Ting Wu
Ching-Heng Lin
Yi-Hsuan Lin
Ya-Chi Hsu
Chung-Ting Hsu
Ming-Chih Lin
Maternal risk factors for preterm birth in Taiwan, a nationwide population-based cohort study
Pediatrics and Neonatology
premature birth
maternal health
pregnancy
high-risk
pregnancy complications
perinatology
title Maternal risk factors for preterm birth in Taiwan, a nationwide population-based cohort study
title_full Maternal risk factors for preterm birth in Taiwan, a nationwide population-based cohort study
title_fullStr Maternal risk factors for preterm birth in Taiwan, a nationwide population-based cohort study
title_full_unstemmed Maternal risk factors for preterm birth in Taiwan, a nationwide population-based cohort study
title_short Maternal risk factors for preterm birth in Taiwan, a nationwide population-based cohort study
title_sort maternal risk factors for preterm birth in taiwan a nationwide population based cohort study
topic premature birth
maternal health
pregnancy
high-risk
pregnancy complications
perinatology
url http://www.sciencedirect.com/science/article/pii/S1875957223001225
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