Lipid metabolism-mediated fertility decline in male mice exposed to Fluorene-9-bisphenol: An integrated DNA methylation and transcriptomics analysis

Lipid metabolism-mediated fertility decline in male mice exposed to Fluorene-9-bisphenol: An integrated DNA methylation and transcriptomics analysis

Fluorene-9-bisphenol (BHPF), a widely recognized alternative to bisphenol A (BPA), has been increasingly used in a wide range of industries. However, despite numerous studies, the direct mechanism underlying its male reproductive toxicity remains poorly understood. Here, a BHPF-exposed mouse model w...

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Bibliographic Details
Main Authors: Danni Jiang, Yang Yang, Xiaojuan Han, Qianni Li, Yingxiu Ma, Jun Jiao, Lan Chao
Format: Article
Language:English
Published: Elsevier 2025-04-01
Series:Ecotoxicology and Environmental Safety
Subjects:
BHPF
Male reproductive toxicity
DNA methylome
RNA-seq
Multi-omics analysis
Online Access:http://www.sciencedirect.com/science/article/pii/S014765132500452X
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