Clinicopathological and molecular analyses of uterine carcinosarcomas using next-generation sequencing: A single-center experience

Clinicopathological and molecular analyses of uterine carcinosarcomas using next-generation sequencing: A single-center experience

Background: Uterine carcinosarcomas (UCS) constitute 3–4% of all uterine malignancies and 16% of deaths caused due to uterine neoplasms. Aim: In this study, we aimed to perform DNA-based mutation analysis in 12 genes (KRAS, NRAS, EGFR, C-KIT, BRAF, PDGFRA, ALK, ERBB2, ERBB3, ESR1, RAF1, PIK3CA) to d...

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Main Authors: Ezgi Genç Erdoğan, Tülin D. Yalta, Nuray Can, Necdet Süt, Ebru Taştekin, Ufuk Usta, Fulya Öz Puyan, Fatma E. Usturalı Keskin, Busem B. Kurt
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2023-07-01
Series:Indian Journal of Pathology and Microbiology
Subjects:
molecular analysis
molecular variations
mutations
next-generation sequencing
uterine carcinosarcoma
Online Access:https://journals.lww.com/10.4103/ijpm.ijpm_777_21
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