Insulin-Related Skin Lipohypertrophy in Type Two Diabetes: A Clinical Study of a Case Series, with Ultrasonographic and Histopathologic Implications

Insulin-Related Skin Lipohypertrophy in Type Two Diabetes: A Clinical Study of a Case Series, with Ultrasonographic and Histopathologic Implications

Introduction: The most frequent local complication of insulin injection is the occurrence of subcutaneous nodules due to incorrect injection technique. Injection into nodules negatively impacts metabolic compensation and the requirement for greater insulin doses due to its partial and erratic absorp...

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Main Authors: Sandro Gentile, Felice Strollo, Giuseppina Guarino, Andrea Ronchi, Ersilia Satta, Teresa Della-Corte, Elisabetta Fulgione, Graziella Babino, Edi Mattera, Emilia Martedì, Roberta Di Martino, Raffaella Fiorentino, Roberta Porcini, Carmine Romano, Maria Chiarello, Giuseppe Caccavale, Renato Franco, Giuseppe Argenziano
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Diabetology
Subjects:
insulin-induced lipohypertrophy
histopathology
diabetes complications
insulin-derived amyloidosis
injection technique
Online Access:https://www.mdpi.com/2673-4540/5/7/53
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