Study of the Elevation of Galectin-3 Level in Plasma Patients with Inflammatory Bowel Disease in Babylon Province
Background: Inflammatory bowel disease is a collection of illnesses that mainly affect the colon and small intestine, the most prevalent types being Crohn’s disease and ulcerative colitis. Carbohydrate-binding proteins (also known as galectins) have been shown to play an essential role in the regula...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2025-01-01
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| Series: | Medical Journal of Babylon |
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| Online Access: | https://doi.org/10.4103/MJBL.MJBL_271_23 |
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| author | Arkan Khanjar Nasrullah Ban Mahmood Shaker Al-joda Hassan Salim Aljumaily |
| author_facet | Arkan Khanjar Nasrullah Ban Mahmood Shaker Al-joda Hassan Salim Aljumaily |
| author_sort | Arkan Khanjar Nasrullah |
| collection | DOAJ |
| description | Background: Inflammatory bowel disease is a collection of illnesses that mainly affect the colon and small intestine, the most prevalent types being Crohn’s disease and ulcerative colitis. Carbohydrate-binding proteins (also known as galectins) have been shown to play an essential role in the regulation of both innate and adaptive immune responses. Objective: The aim of this study was to measure the amount of galectin-3 and look at any potential links between the protein and iron, and vitamin E in inflammatory bowel illness in Babylon province. Materials and Methods: Galectin-3 levels were evaluated in 100 people: 50 with inflammatory bowel disease and 50 with healthy people. The study participants and the healthy controls varied in age from 15 to 65. The enzyme-linked immunosorbent assay (ELISA) method measured Galectin-3 and vitamin E while Iron was in the spectrophotometer in the serum. Results: The serum Galectin-3 was greater in IBD patients than in controls (P = 0.01). In contrast, the current study discovered a negative association between Galectin-3 and iron in IBD patients (P = 0.05) and a non-significant relationship between Galectin-3 and vitamin E in IBD patients (P > 0.05). Conclusion: There is a significant association between IBD and high Galectin-3 levels in Babylon province patients. |
| format | Article |
| id | doaj-art-8c68cb5ce0d94c0bbeebd468a9dad6b2 |
| institution | OA Journals |
| issn | 1812-156X 2312-6760 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Medical Journal of Babylon |
| spelling | doaj-art-8c68cb5ce0d94c0bbeebd468a9dad6b22025-08-20T01:51:41ZengWolters Kluwer Medknow PublicationsMedical Journal of Babylon1812-156X2312-67602025-01-01221939710.4103/MJBL.MJBL_271_23Study of the Elevation of Galectin-3 Level in Plasma Patients with Inflammatory Bowel Disease in Babylon ProvinceArkan Khanjar NasrullahBan Mahmood Shaker Al-jodaHassan Salim AljumailyBackground: Inflammatory bowel disease is a collection of illnesses that mainly affect the colon and small intestine, the most prevalent types being Crohn’s disease and ulcerative colitis. Carbohydrate-binding proteins (also known as galectins) have been shown to play an essential role in the regulation of both innate and adaptive immune responses. Objective: The aim of this study was to measure the amount of galectin-3 and look at any potential links between the protein and iron, and vitamin E in inflammatory bowel illness in Babylon province. Materials and Methods: Galectin-3 levels were evaluated in 100 people: 50 with inflammatory bowel disease and 50 with healthy people. The study participants and the healthy controls varied in age from 15 to 65. The enzyme-linked immunosorbent assay (ELISA) method measured Galectin-3 and vitamin E while Iron was in the spectrophotometer in the serum. Results: The serum Galectin-3 was greater in IBD patients than in controls (P = 0.01). In contrast, the current study discovered a negative association between Galectin-3 and iron in IBD patients (P = 0.05) and a non-significant relationship between Galectin-3 and vitamin E in IBD patients (P > 0.05). Conclusion: There is a significant association between IBD and high Galectin-3 levels in Babylon province patients.https://doi.org/10.4103/MJBL.MJBL_271_23galectin-3inflammatory bowel diseaseironvitamin e |
| spellingShingle | Arkan Khanjar Nasrullah Ban Mahmood Shaker Al-joda Hassan Salim Aljumaily Study of the Elevation of Galectin-3 Level in Plasma Patients with Inflammatory Bowel Disease in Babylon Province Medical Journal of Babylon galectin-3 inflammatory bowel disease iron vitamin e |
| title | Study of the Elevation of Galectin-3 Level in Plasma Patients with Inflammatory Bowel Disease in Babylon Province |
| title_full | Study of the Elevation of Galectin-3 Level in Plasma Patients with Inflammatory Bowel Disease in Babylon Province |
| title_fullStr | Study of the Elevation of Galectin-3 Level in Plasma Patients with Inflammatory Bowel Disease in Babylon Province |
| title_full_unstemmed | Study of the Elevation of Galectin-3 Level in Plasma Patients with Inflammatory Bowel Disease in Babylon Province |
| title_short | Study of the Elevation of Galectin-3 Level in Plasma Patients with Inflammatory Bowel Disease in Babylon Province |
| title_sort | study of the elevation of galectin 3 level in plasma patients with inflammatory bowel disease in babylon province |
| topic | galectin-3 inflammatory bowel disease iron vitamin e |
| url | https://doi.org/10.4103/MJBL.MJBL_271_23 |
| work_keys_str_mv | AT arkankhanjarnasrullah studyoftheelevationofgalectin3levelinplasmapatientswithinflammatoryboweldiseaseinbabylonprovince AT banmahmoodshakeraljoda studyoftheelevationofgalectin3levelinplasmapatientswithinflammatoryboweldiseaseinbabylonprovince AT hassansalimaljumaily studyoftheelevationofgalectin3levelinplasmapatientswithinflammatoryboweldiseaseinbabylonprovince |