Macrophage Transcriptomic Alterations Driven by Alphavirus-Based Cancer Immunotherapy Vectors

Macrophage Transcriptomic Alterations Driven by Alphavirus-Based Cancer Immunotherapy Vectors

Cancer cells promote the polarisation of tumour-associated macrophages (TAMs) into pro-tumorigenic M2-like phenotype, contributing to cancer progression. Reprogramming TAMs by viral immunotherapy vectors represents a promising strategy for cancer therapy. However, the factors driving macrophage repr...

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Bibliographic Details
Main Authors: Ksenija Korotkaja, Darija Lapina, Zhanna Rudevica, Anna Zajakina
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:Journal of Immunology Research
Online Access:http://dx.doi.org/10.1155/jimr/6573891
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