Genome-wide maps of highly-similar intrachromosomal repeats that can mediate ectopic recombination in three human genome assemblies

Genome-wide maps of highly-similar intrachromosomal repeats that can mediate ectopic recombination in three human genome assemblies

Summary: Repeated sequences spread throughout the genome play important roles in shaping the structure of chromosomes and facilitating the generation of new genomic variation through structural rearrangements. Several mechanisms of structural variation formation use shared nucleotide similarity betw...

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Bibliographic Details
Main Authors: Luis Fernandez-Luna, Carlos Aguilar-Perez, Christopher M. Grochowski, Michele G. Mehaffey, Claudia M.B. Carvalho, Claudia Gonzaga-Jauregui
Format: Article
Language:English
Published: Elsevier 2025-04-01
Series:HGG Advances
Subjects:
repeats
genomic rearrangements
structural variation
ectopic recombination
microhomology
segmental duplications
Online Access:http://www.sciencedirect.com/science/article/pii/S2666247724001362
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http://www.sciencedirect.com/science/article/pii/S2666247724001362

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