Comparing the biopsy strategies of prostate cancer: a systematic review and network meta-analysis
Abstract The introduction of three kinds of magnetic resonance imaging-guided prostate biopsies (MRI-PB) has changed the paradigm regarding prostate biopsies (PB). We aimed to compare and rank PB strategies to provide the latest evidence of PB option for prostate cancer (PCa) diagnosis. We searched...
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| Format: | Article |
| Language: | English |
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BMC
2025-04-01
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| Series: | BMC Cancer |
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| Online Access: | https://doi.org/10.1186/s12885-025-14203-y |
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| author | Yiqi Huang Cailiu Wei Fenjuan Chen Yanling Zhang Feifei Pu |
| author_facet | Yiqi Huang Cailiu Wei Fenjuan Chen Yanling Zhang Feifei Pu |
| author_sort | Yiqi Huang |
| collection | DOAJ |
| description | Abstract The introduction of three kinds of magnetic resonance imaging-guided prostate biopsies (MRI-PB) has changed the paradigm regarding prostate biopsies (PB). We aimed to compare and rank PB strategies to provide the latest evidence of PB option for prostate cancer (PCa) diagnosis. We searched PubMed, the Cochrane Library Central, Scopus, Embase and the reference lists of relevant articles for randomized controlled trials published up to Dec, 2024, of different PB strategies. Finally, 24 randomized trials were included. Eleven PB strategies published were considered. For overall PCa detection rates exclusively previously negative biopsy patients, we found robust improvements of 3.92 (95% CI: 2.17–6.41) for MRI-cognitive- and 1.78 (95% CI: 1.02–3.07) for MRI/TRUS- compared to TRUS(10–12)-PB. For PCa detection when prostate volume ≤ 50 mm3, only MRI/TRUS- was significantly effective than TRUS(10–12)-PB (OR 1.78, 95% CI: 1.0–2.89). Our study indicated that MRI-cognitive-PB was associated with better overall PCa detection rates compared with TRUS(10–12)-PB, but it had no remarkable advantages in csPCa and ciPCa detection. More head-to-head comparisons of MRI-PB techniques are needed in the future. |
| format | Article |
| id | doaj-art-8c4ec910f01948d1bd2cac15b4b390c9 |
| institution | Kabale University |
| issn | 1471-2407 |
| language | English |
| publishDate | 2025-04-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Cancer |
| spelling | doaj-art-8c4ec910f01948d1bd2cac15b4b390c92025-08-20T03:52:24ZengBMCBMC Cancer1471-24072025-04-0125111210.1186/s12885-025-14203-yComparing the biopsy strategies of prostate cancer: a systematic review and network meta-analysisYiqi Huang0Cailiu Wei1Fenjuan Chen2Yanling Zhang3Feifei Pu4Department of Nephrology, Shaoxing Second HospitalAffiliated Hospital of Youjiang Medical University for NationalitiesDepartment of Internal Medicine, Shaoxing Second HospitalDepartment of Nephrology, Shaoxing Second HospitalDepartment of Ultrasonic, Shaoxing Second HospitalAbstract The introduction of three kinds of magnetic resonance imaging-guided prostate biopsies (MRI-PB) has changed the paradigm regarding prostate biopsies (PB). We aimed to compare and rank PB strategies to provide the latest evidence of PB option for prostate cancer (PCa) diagnosis. We searched PubMed, the Cochrane Library Central, Scopus, Embase and the reference lists of relevant articles for randomized controlled trials published up to Dec, 2024, of different PB strategies. Finally, 24 randomized trials were included. Eleven PB strategies published were considered. For overall PCa detection rates exclusively previously negative biopsy patients, we found robust improvements of 3.92 (95% CI: 2.17–6.41) for MRI-cognitive- and 1.78 (95% CI: 1.02–3.07) for MRI/TRUS- compared to TRUS(10–12)-PB. For PCa detection when prostate volume ≤ 50 mm3, only MRI/TRUS- was significantly effective than TRUS(10–12)-PB (OR 1.78, 95% CI: 1.0–2.89). Our study indicated that MRI-cognitive-PB was associated with better overall PCa detection rates compared with TRUS(10–12)-PB, but it had no remarkable advantages in csPCa and ciPCa detection. More head-to-head comparisons of MRI-PB techniques are needed in the future.https://doi.org/10.1186/s12885-025-14203-yProstate cancerBiopsyNetwork meta-analysis |
| spellingShingle | Yiqi Huang Cailiu Wei Fenjuan Chen Yanling Zhang Feifei Pu Comparing the biopsy strategies of prostate cancer: a systematic review and network meta-analysis BMC Cancer Prostate cancer Biopsy Network meta-analysis |
| title | Comparing the biopsy strategies of prostate cancer: a systematic review and network meta-analysis |
| title_full | Comparing the biopsy strategies of prostate cancer: a systematic review and network meta-analysis |
| title_fullStr | Comparing the biopsy strategies of prostate cancer: a systematic review and network meta-analysis |
| title_full_unstemmed | Comparing the biopsy strategies of prostate cancer: a systematic review and network meta-analysis |
| title_short | Comparing the biopsy strategies of prostate cancer: a systematic review and network meta-analysis |
| title_sort | comparing the biopsy strategies of prostate cancer a systematic review and network meta analysis |
| topic | Prostate cancer Biopsy Network meta-analysis |
| url | https://doi.org/10.1186/s12885-025-14203-y |
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