Progesterone and progesterone receptors in breast cancer: past, present, and future
The history of progesterone and progesterone receptors (PR) in breast cancer is as great, as controversial. In this review, we summarize the early history of PR research in breast cancer, debunk the myth that progesterone causes cancer, discuss recent discoveries in PR regulating cellular heterogene...
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| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | Russian |
| Published: |
ABV-press
2025-03-01
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| Series: | Опухоли женской репродуктивной системы |
| Subjects: | |
| Online Access: | https://ojrs.abvpress.ru/ojrs/article/view/1319 |
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| Summary: | The history of progesterone and progesterone receptors (PR) in breast cancer is as great, as controversial. In this review, we summarize the early history of PR research in breast cancer, debunk the myth that progesterone causes cancer, discuss recent discoveries in PR regulating cellular heterogeneity, attempt to reconcile theories that PR play “good” and “bad” role in tumorigenesis, and discuss new directions that may help elucidate the role of this puzzling hormone and its receptors. |
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| ISSN: | 1994-4098 1999-8627 |