DKK3 promotes adipogenic differentiation of stem cells by inhibiting Wnt/β-catenin signaling pathway related gene expression and mitochondrial autophagy function

DKK3 promotes adipogenic differentiation of stem cells by inhibiting Wnt/β-catenin signaling pathway related gene expression and mitochondrial autophagy function

ABSTRACT: Mesenchymal stem cells can differentiate into adipocyte precursor cells, and the balance of stem cell differentiation determines the quantity of adipocytes. Early-stage adipose tissue expression profiling revealed abnormal expression of DKK3 in the high-fat group. Moreover, DKK3 is enriche...

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Bibliographic Details
Main Authors: Ze Zhang, Haohui Wei, Tao Lin, Changbin Zhao, Yongxiang Song, Yuelin Deng, Yiqing Sun, Yongxia Zhao, Qingbin Luo, Xiquan Zhang, Dexiang Zhang, Hongmei Li
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Poultry Science
Subjects:
chicken
BMSCs
Wnt-βcatenin signaling pathway
lipogenic differentiation
mitochondria
DKK3
Online Access:http://www.sciencedirect.com/science/article/pii/S0032579124008368
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