Pharmacokinetic and Bioequivalence Study of Telzap AM<sup>®</sup> (Telmisartan/amlodipine Fixed-dose Combination) and Coadministered Mikardis<sup>®</sup> (Telmisartan) and Norvask<sup>®</sup> (Amlodipine) in Healthy Subjects

Pharmacokinetic and Bioequivalence Study of Telzap AM<sup>®</sup> (Telmisartan/amlodipine Fixed-dose Combination) and Coadministered Mikardis<sup>®</sup> (Telmisartan) and Norvask<sup>®</sup> (Amlodipine) in Healthy Subjects

Introduction. A fixed dose combination of telmisartan and amlodipine is widely used in clinical practice during hypertension treatment. Combination of telmisartan and amlodipine demonstrates potentiating synergistic effect on blood pressure decrease. A bioequivalence study of Telzap® AM with coadmin...

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Bibliographic Details
Main Authors: V. Kubesh, A. L. Khokhlov, A. M. Shitova, Yu. A. Dzhurko, V. I. Kazey, A. A. Khokhlov, A. E. Miroshnikov, O. V. Lebedeva, I. K. Klaus, A. V. Zyatenkov
Format: Article
Language:Russian
Published: LLC Center of Pharmaceutical Analytics (LLC «CPHA») 2020-11-01
Series:Разработка и регистрация лекарственных средств
Subjects:
telmisartan
amlodipine
pharmacokinetics
bioequivalence
Online Access:https://www.pharmjournal.ru/jour/article/view/824
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