Are all tuberculosis deaths correctly attributed due to tuberculosis? Analysis of causes of death (COD) using verbal autopsy: A cross-sectional study in Puducherry

Background: State Task Force National Tuberculosis Elimination Programme (STF-NTEP) wanted to ascertain the cause of death of tuberculosis (TB) patients was due to TB. Hence, this study was done to determine the cause of death among TB patients using verbal autopsy. Material and Method: The communit...

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Main Authors: Reenaa Mohan, M Rajalakshmi, G Kalaiselvan
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2025-01-01
Series:Journal of Family Medicine and Primary Care
Subjects:
Online Access:https://journals.lww.com/10.4103/jfmpc.jfmpc_1108_24
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author Reenaa Mohan
M Rajalakshmi
G Kalaiselvan
author_facet Reenaa Mohan
M Rajalakshmi
G Kalaiselvan
author_sort Reenaa Mohan
collection DOAJ
description Background: State Task Force National Tuberculosis Elimination Programme (STF-NTEP) wanted to ascertain the cause of death of tuberculosis (TB) patients was due to TB. Hence, this study was done to determine the cause of death among TB patients using verbal autopsy. Material and Method: The community-based cross-sectional study was conducted among the closest caregivers of the reported TB death cases using a verbal autopsy questionnaire. A list of TB deaths was extracted from Puducherry’s State Tuberculosis Office (STO). The VA questionnaires were reviewed by two trained faculties and experts independently who were also asked to code the cause of death according to the International Classification of Diseases – 10th Revision. Data were analysed using the SPSS software receiver operator curve (ROC) curve and Cohen’s kappa statistics with 95% confidence interval (CI) were applied to compare agreement between the raters. Results: Out of 307 TB deaths, 143 were contacted and the remaining were migrated, missing or not available. Among them 34.9% of the declared TB deaths are not due to TB. Cohen’s kappa = 0.4; 95% CI: (0.858–0.985) showed moderate agreement between the raters. Experts’ review was used as a reference standard to compare rater agreements. The Predictive accuracy of Rater 2 (area under the curve [AUC] −0.953; P value <0.001) was slightly higher than Rater 1 (AUC −0.942; P value <0.001). Conclusion: The findings of the study have clearly indicated that 34.9% of the declared TB deaths are not due to TB.
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spelling doaj-art-8bfa249f57fe4789a6fae93bf4664edf2025-02-11T13:53:12ZengWolters Kluwer Medknow PublicationsJournal of Family Medicine and Primary Care2249-48632278-71352025-01-0114129029510.4103/jfmpc.jfmpc_1108_24Are all tuberculosis deaths correctly attributed due to tuberculosis? Analysis of causes of death (COD) using verbal autopsy: A cross-sectional study in PuducherryReenaa MohanM RajalakshmiG KalaiselvanBackground: State Task Force National Tuberculosis Elimination Programme (STF-NTEP) wanted to ascertain the cause of death of tuberculosis (TB) patients was due to TB. Hence, this study was done to determine the cause of death among TB patients using verbal autopsy. Material and Method: The community-based cross-sectional study was conducted among the closest caregivers of the reported TB death cases using a verbal autopsy questionnaire. A list of TB deaths was extracted from Puducherry’s State Tuberculosis Office (STO). The VA questionnaires were reviewed by two trained faculties and experts independently who were also asked to code the cause of death according to the International Classification of Diseases – 10th Revision. Data were analysed using the SPSS software receiver operator curve (ROC) curve and Cohen’s kappa statistics with 95% confidence interval (CI) were applied to compare agreement between the raters. Results: Out of 307 TB deaths, 143 were contacted and the remaining were migrated, missing or not available. Among them 34.9% of the declared TB deaths are not due to TB. Cohen’s kappa = 0.4; 95% CI: (0.858–0.985) showed moderate agreement between the raters. Experts’ review was used as a reference standard to compare rater agreements. The Predictive accuracy of Rater 2 (area under the curve [AUC] −0.953; P value <0.001) was slightly higher than Rater 1 (AUC −0.942; P value <0.001). Conclusion: The findings of the study have clearly indicated that 34.9% of the declared TB deaths are not due to TB.https://journals.lww.com/10.4103/jfmpc.jfmpc_1108_24auccodkapparoctb deathsverbal autopsy
spellingShingle Reenaa Mohan
M Rajalakshmi
G Kalaiselvan
Are all tuberculosis deaths correctly attributed due to tuberculosis? Analysis of causes of death (COD) using verbal autopsy: A cross-sectional study in Puducherry
Journal of Family Medicine and Primary Care
auc
cod
kappa
roc
tb deaths
verbal autopsy
title Are all tuberculosis deaths correctly attributed due to tuberculosis? Analysis of causes of death (COD) using verbal autopsy: A cross-sectional study in Puducherry
title_full Are all tuberculosis deaths correctly attributed due to tuberculosis? Analysis of causes of death (COD) using verbal autopsy: A cross-sectional study in Puducherry
title_fullStr Are all tuberculosis deaths correctly attributed due to tuberculosis? Analysis of causes of death (COD) using verbal autopsy: A cross-sectional study in Puducherry
title_full_unstemmed Are all tuberculosis deaths correctly attributed due to tuberculosis? Analysis of causes of death (COD) using verbal autopsy: A cross-sectional study in Puducherry
title_short Are all tuberculosis deaths correctly attributed due to tuberculosis? Analysis of causes of death (COD) using verbal autopsy: A cross-sectional study in Puducherry
title_sort are all tuberculosis deaths correctly attributed due to tuberculosis analysis of causes of death cod using verbal autopsy a cross sectional study in puducherry
topic auc
cod
kappa
roc
tb deaths
verbal autopsy
url https://journals.lww.com/10.4103/jfmpc.jfmpc_1108_24
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