Evaluation of extracts from used Xpert MTB/RIF cartridges for detection of resistance to second-line anti-tuberculosis drugs in patients with multidrug-resistant tuberculosis in Ethiopia

Evaluation of extracts from used Xpert MTB/RIF cartridges for detection of resistance to second-line anti-tuberculosis drugs in patients with multidrug-resistant tuberculosis in Ethiopia

Abstract Background Early and accurate diagnosis of drug resistance, including resistance to second-line anti-tuberculosis (TB) drugs, is crucial for the effective control and management of pre-extensively drug-resistant TB (pre-XDR-TB) and extensively drug-resistant TB (XDR-TB). The Xpert MTB/XDR a...

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Bibliographic Details
Main Authors: Tilahun Ketema, Mulualem Tadesse, Zegeye Bonsa, Getu Balay, Wakjira Kebede, Mekidim Mekonnen, Gemeda Abebe
Format: Article
Language:English
Published: BMC 2025-01-01
Series:BMC Microbiology
Subjects:
Genotypic drug susceptibility testing
Cartridge extract
Line probe assay
Online Access:https://doi.org/10.1186/s12866-025-03746-6
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