Spontaneous Tumour Lysis Syndrome in a Multiple Myeloma
The tumor lysis syndrome (TLS) is a collection of metabolic abnormalities that occur in consequence of the release of intracellular contents following lysis of tumor cells. TLS occurs spontaneously or after chemotherapy. Spontaneous TLS is uncommon occurrence in multiple myeloma (MM). We define a ca...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2016-01-01
|
| Series: | Case Reports in Medicine |
| Online Access: | http://dx.doi.org/10.1155/2016/9620520 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850212967892647936 |
|---|---|
| author | Can Huzmeli Eylem Eliacik Mustafa Saglam Baris Doner Ferhan Candan |
| author_facet | Can Huzmeli Eylem Eliacik Mustafa Saglam Baris Doner Ferhan Candan |
| author_sort | Can Huzmeli |
| collection | DOAJ |
| description | The tumor lysis syndrome (TLS) is a collection of metabolic abnormalities that occur in consequence of the release of intracellular contents following lysis of tumor cells. TLS occurs spontaneously or after chemotherapy. Spontaneous TLS is uncommon occurrence in multiple myeloma (MM). We define a case of a 70-year-old woman patient who was found to have MM with spontaneous TLS, following a compression fracture of the T-12 vertebrae. While serum uric acid and phosphorous levels were high, low calcium levels were identified. There were also acute kidney injury and metabolic acidosis. Upon the diagnosis of TLS, she was treated with hydration, allopurinol, sodium bicarbonate, and calcium gluconate. The improvement of her laboratory data was observed. We submitted this case in order to draw attention to the presentation of MM with spontaneous TLS. |
| format | Article |
| id | doaj-art-8befceddf6184e7bab9e8189d2bec734 |
| institution | OA Journals |
| issn | 1687-9627 1687-9635 |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Medicine |
| spelling | doaj-art-8befceddf6184e7bab9e8189d2bec7342025-08-20T02:09:13ZengWileyCase Reports in Medicine1687-96271687-96352016-01-01201610.1155/2016/96205209620520Spontaneous Tumour Lysis Syndrome in a Multiple MyelomaCan Huzmeli0Eylem Eliacik1Mustafa Saglam2Baris Doner3Ferhan Candan4Necip Fazıl City Hospital, Department of Nephrology, Kahramanmaras, TurkeyNecip Fazıl City Hospital, Department of Hematology, Kahramanmaras, TurkeyNecip Fazıl City Hospital, Department of Nephrology, Kahramanmaras, TurkeyNecip Fazıl City Hospital, Department of Nephrology, Kahramanmaras, TurkeyDepartment of Nephrology, Cumhuriyet University, Sivas, TurkeyThe tumor lysis syndrome (TLS) is a collection of metabolic abnormalities that occur in consequence of the release of intracellular contents following lysis of tumor cells. TLS occurs spontaneously or after chemotherapy. Spontaneous TLS is uncommon occurrence in multiple myeloma (MM). We define a case of a 70-year-old woman patient who was found to have MM with spontaneous TLS, following a compression fracture of the T-12 vertebrae. While serum uric acid and phosphorous levels were high, low calcium levels were identified. There were also acute kidney injury and metabolic acidosis. Upon the diagnosis of TLS, she was treated with hydration, allopurinol, sodium bicarbonate, and calcium gluconate. The improvement of her laboratory data was observed. We submitted this case in order to draw attention to the presentation of MM with spontaneous TLS.http://dx.doi.org/10.1155/2016/9620520 |
| spellingShingle | Can Huzmeli Eylem Eliacik Mustafa Saglam Baris Doner Ferhan Candan Spontaneous Tumour Lysis Syndrome in a Multiple Myeloma Case Reports in Medicine |
| title | Spontaneous Tumour Lysis Syndrome in a Multiple Myeloma |
| title_full | Spontaneous Tumour Lysis Syndrome in a Multiple Myeloma |
| title_fullStr | Spontaneous Tumour Lysis Syndrome in a Multiple Myeloma |
| title_full_unstemmed | Spontaneous Tumour Lysis Syndrome in a Multiple Myeloma |
| title_short | Spontaneous Tumour Lysis Syndrome in a Multiple Myeloma |
| title_sort | spontaneous tumour lysis syndrome in a multiple myeloma |
| url | http://dx.doi.org/10.1155/2016/9620520 |
| work_keys_str_mv | AT canhuzmeli spontaneoustumourlysissyndromeinamultiplemyeloma AT eylemeliacik spontaneoustumourlysissyndromeinamultiplemyeloma AT mustafasaglam spontaneoustumourlysissyndromeinamultiplemyeloma AT barisdoner spontaneoustumourlysissyndromeinamultiplemyeloma AT ferhancandan spontaneoustumourlysissyndromeinamultiplemyeloma |