Rate–Pressure Product and Cardiac Cachexia in End-Stage Heart Failure
To address the effect of cardiac cachexia on the failing heart, we analyzed serial home-care monitoring of the rate–pressure product, as substitution of myocardial oxygen consumption, over 218 days in a 79-year-old man with a catecholamine-dependent end-stage dilated cardiomyopathy. At the end of hi...
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| Format: | Article |
| Language: | English |
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American College of Physicians
2024-09-01
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| Series: | Annals of Internal Medicine: Clinical Cases |
| Online Access: | https://www.acpjournals.org/doi/10.7326/aimcc.2023.1465 |
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| _version_ | 1849698924678348800 |
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| author | Makoto Suzuki Manami Kishimoto Tomomi Horita Akira Fujii Satoru Hamada |
| author_facet | Makoto Suzuki Manami Kishimoto Tomomi Horita Akira Fujii Satoru Hamada |
| author_sort | Makoto Suzuki |
| collection | DOAJ |
| description | To address the effect of cardiac cachexia on the failing heart, we analyzed serial home-care monitoring of the rate–pressure product, as substitution of myocardial oxygen consumption, over 218 days in a 79-year-old man with a catecholamine-dependent end-stage dilated cardiomyopathy. At the end of his home-care visits, his body weight decreased to 37 kg from 55.2 kg (baseline). We found a linear reduction of the rate–pressure product accompanied by weight loss (r2 = 0.186; P = 0.0001), implying the progression of cardiac cachexia as a possible role in reducing myocardial oxygen consumption, which would mitigate energy deprivation of the failing heart. |
| format | Article |
| id | doaj-art-8bdce0f822a9437dbf99ce20702f75d0 |
| institution | DOAJ |
| issn | 2767-7664 |
| language | English |
| publishDate | 2024-09-01 |
| publisher | American College of Physicians |
| record_format | Article |
| series | Annals of Internal Medicine: Clinical Cases |
| spelling | doaj-art-8bdce0f822a9437dbf99ce20702f75d02025-08-20T03:18:46ZengAmerican College of PhysiciansAnnals of Internal Medicine: Clinical Cases2767-76642024-09-013910.7326/aimcc.2023.1465Rate–Pressure Product and Cardiac Cachexia in End-Stage Heart FailureMakoto Suzuki0Manami Kishimoto1Tomomi Horita2Akira Fujii3Satoru Hamada41Hoshinooka Cardiovascular Clinic, Matsuyama, Japan1Hoshinooka Cardiovascular Clinic, Matsuyama, Japan1Hoshinooka Cardiovascular Clinic, Matsuyama, Japan1Hoshinooka Cardiovascular Clinic, Matsuyama, Japan2Orange Visiting Nursing Station, Matsuyama, JapanTo address the effect of cardiac cachexia on the failing heart, we analyzed serial home-care monitoring of the rate–pressure product, as substitution of myocardial oxygen consumption, over 218 days in a 79-year-old man with a catecholamine-dependent end-stage dilated cardiomyopathy. At the end of his home-care visits, his body weight decreased to 37 kg from 55.2 kg (baseline). We found a linear reduction of the rate–pressure product accompanied by weight loss (r2 = 0.186; P = 0.0001), implying the progression of cardiac cachexia as a possible role in reducing myocardial oxygen consumption, which would mitigate energy deprivation of the failing heart.https://www.acpjournals.org/doi/10.7326/aimcc.2023.1465 |
| spellingShingle | Makoto Suzuki Manami Kishimoto Tomomi Horita Akira Fujii Satoru Hamada Rate–Pressure Product and Cardiac Cachexia in End-Stage Heart Failure Annals of Internal Medicine: Clinical Cases |
| title | Rate–Pressure Product and Cardiac Cachexia in End-Stage Heart Failure |
| title_full | Rate–Pressure Product and Cardiac Cachexia in End-Stage Heart Failure |
| title_fullStr | Rate–Pressure Product and Cardiac Cachexia in End-Stage Heart Failure |
| title_full_unstemmed | Rate–Pressure Product and Cardiac Cachexia in End-Stage Heart Failure |
| title_short | Rate–Pressure Product and Cardiac Cachexia in End-Stage Heart Failure |
| title_sort | rate pressure product and cardiac cachexia in end stage heart failure |
| url | https://www.acpjournals.org/doi/10.7326/aimcc.2023.1465 |
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