Allergic Contact Dermatitis to Acrylates: A Study Among Manicurists and Clients

The study aimеd to investigate the association between the professional environment and hypersensitivity reactions to various contact allergens, features of the clinical course, and types of allergic contact dermatitis (ACD) in 34 manicurists and ten service users. The analysis was based on the data...

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Main Authors: Klimentina Gospodinova, Adriana Angelova, Malena Gergovska, Daniela Grozeva
Format: Article
Language:English
Published: Medical University - Pleven 2023-12-01
Series:Journal of Biomedical & Clinical Research
Subjects:
Online Access:https://jbcr.arphahub.com/article/34699/download/pdf/
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author Klimentina Gospodinova
Adriana Angelova
Malena Gergovska
Daniela Grozeva
author_facet Klimentina Gospodinova
Adriana Angelova
Malena Gergovska
Daniela Grozeva
author_sort Klimentina Gospodinova
collection DOAJ
description The study aimеd to investigate the association between the professional environment and hypersensitivity reactions to various contact allergens, features of the clinical course, and types of allergic contact dermatitis (ACD) in 34 manicurists and ten service users. The analysis was based on the data on length of professional experience, localisation of rashes, clinical diagnoses and allergens, and the cause of positive reactions in epicutaneous testing. Pathological skin changes most often affected the upper limbs (hands, palms, fingers). As a diagnosis, the frequency of ACD was the highest – 79.4%, followed by that of dyshidrotic eczema (DE) – 17.6%, which also determines the highest percentage of dermatitis on the upper limbs (97%). Of the patients, 47.1% had a history of the disease for up to one year. For manicurists, the results of patch tests with the specialised MH-1000 series showed the highest frequency of positive reactions to 2-Hydroxyethyl methacrylate (2-HEMA) and 2-Hydroxypropyl methacrylate (2-HPMA) – 88.88% each, Ethylene glycol dimethacrylate (EGDMA) – 83.33% and 2-Hydroxyethyl acrylate (2-HEA) – 61.11%. After combining data for manicurists and clients, correlation analysis found a significant effect on the development of ACD to 2-HPMA (p=0.003) and EGDMA (p=0.005), as well as for hand dermatitis to 2-HEMA (p=0.05) and 2-HEA (p=0.044).
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publishDate 2023-12-01
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spelling doaj-art-8bdba31b0eb8426ebef5d8f3e20c96e02025-08-20T03:35:36ZengMedical University - PlevenJournal of Biomedical & Clinical Research1313-90532023-12-0116218619310.2478/jbcr-2023-002534699Allergic Contact Dermatitis to Acrylates: A Study Among Manicurists and ClientsKlimentina GospodinovaAdriana AngelovaMalena GergovskaDaniela GrozevaThe study aimеd to investigate the association between the professional environment and hypersensitivity reactions to various contact allergens, features of the clinical course, and types of allergic contact dermatitis (ACD) in 34 manicurists and ten service users. The analysis was based on the data on length of professional experience, localisation of rashes, clinical diagnoses and allergens, and the cause of positive reactions in epicutaneous testing. Pathological skin changes most often affected the upper limbs (hands, palms, fingers). As a diagnosis, the frequency of ACD was the highest – 79.4%, followed by that of dyshidrotic eczema (DE) – 17.6%, which also determines the highest percentage of dermatitis on the upper limbs (97%). Of the patients, 47.1% had a history of the disease for up to one year. For manicurists, the results of patch tests with the specialised MH-1000 series showed the highest frequency of positive reactions to 2-Hydroxyethyl methacrylate (2-HEMA) and 2-Hydroxypropyl methacrylate (2-HPMA) – 88.88% each, Ethylene glycol dimethacrylate (EGDMA) – 83.33% and 2-Hydroxyethyl acrylate (2-HEA) – 61.11%. After combining data for manicurists and clients, correlation analysis found a significant effect on the development of ACD to 2-HPMA (p=0.003) and EGDMA (p=0.005), as well as for hand dermatitis to 2-HEMA (p=0.05) and 2-HEA (p=0.044).https://jbcr.arphahub.com/article/34699/download/pdf/allergic contact dermatitismanicurists(meth)ac
spellingShingle Klimentina Gospodinova
Adriana Angelova
Malena Gergovska
Daniela Grozeva
Allergic Contact Dermatitis to Acrylates: A Study Among Manicurists and Clients
Journal of Biomedical & Clinical Research
allergic contact dermatitis
manicurists
(meth)ac
title Allergic Contact Dermatitis to Acrylates: A Study Among Manicurists and Clients
title_full Allergic Contact Dermatitis to Acrylates: A Study Among Manicurists and Clients
title_fullStr Allergic Contact Dermatitis to Acrylates: A Study Among Manicurists and Clients
title_full_unstemmed Allergic Contact Dermatitis to Acrylates: A Study Among Manicurists and Clients
title_short Allergic Contact Dermatitis to Acrylates: A Study Among Manicurists and Clients
title_sort allergic contact dermatitis to acrylates a study among manicurists and clients
topic allergic contact dermatitis
manicurists
(meth)ac
url https://jbcr.arphahub.com/article/34699/download/pdf/
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AT adrianaangelova allergiccontactdermatitistoacrylatesastudyamongmanicuristsandclients
AT malenagergovska allergiccontactdermatitistoacrylatesastudyamongmanicuristsandclients
AT danielagrozeva allergiccontactdermatitistoacrylatesastudyamongmanicuristsandclients