Regression of Hypervascular Nodules in a Patient with Wilson's Disease Awaiting Liver Transplantation

This paper describes the regressive course over one year of hypervascular nodules in a patient with Wilson's disease. CT revealed multiple, enhancing nodules (up to 3 cm in diameter) detected in the liver in the early arterial phase after the administration of intravenous contrast material. Mos...

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Main Authors: Alcindo Pissaia, Hervé Gouya, Olivier Scatton, Filoména Conti, Yvon Calmus
Format: Article
Language:English
Published: Wiley 2009-01-01
Series:Journal of Transplantation
Online Access:http://dx.doi.org/10.1155/2009/597371
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author Alcindo Pissaia
Hervé Gouya
Olivier Scatton
Filoména Conti
Yvon Calmus
author_facet Alcindo Pissaia
Hervé Gouya
Olivier Scatton
Filoména Conti
Yvon Calmus
author_sort Alcindo Pissaia
collection DOAJ
description This paper describes the regressive course over one year of hypervascular nodules in a patient with Wilson's disease. CT revealed multiple, enhancing nodules (up to 3 cm in diameter) detected in the liver in the early arterial phase after the administration of intravenous contrast material. Most of these nodules became isodense in the portal venous phase. After one year of efficient therapy combining d-penicillamine and zinc acetate, most of the nodules had disappeared, while the liver contours had become more regular. To our knowledge, the regression of large hypervascular nodules has not previously been reported in patients with Wilson's disease.
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institution OA Journals
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publishDate 2009-01-01
publisher Wiley
record_format Article
series Journal of Transplantation
spelling doaj-art-8bda20fe8e9447bda947d2d2f8e12f732025-08-20T02:09:14ZengWileyJournal of Transplantation2090-00072090-00152009-01-01200910.1155/2009/597371597371Regression of Hypervascular Nodules in a Patient with Wilson's Disease Awaiting Liver TransplantationAlcindo Pissaia0Hervé Gouya1Olivier Scatton2Filoména Conti3Yvon Calmus4Liver Transplant Unit and Radiology Department, Hôpital Cochin, Université Paris Descartes, 75679 Paris, FranceLiver Transplant Unit and Radiology Department, Hôpital Cochin, Université Paris Descartes, 75679 Paris, FranceLiver Transplant Unit and Radiology Department, Hôpital Cochin, Université Paris Descartes, 75679 Paris, FranceLiver Transplant Unit and Radiology Department, Hôpital Cochin, Université Paris Descartes, 75679 Paris, FranceLiver Transplant Unit and Radiology Department, Hôpital Cochin, Université Paris Descartes, 75679 Paris, FranceThis paper describes the regressive course over one year of hypervascular nodules in a patient with Wilson's disease. CT revealed multiple, enhancing nodules (up to 3 cm in diameter) detected in the liver in the early arterial phase after the administration of intravenous contrast material. Most of these nodules became isodense in the portal venous phase. After one year of efficient therapy combining d-penicillamine and zinc acetate, most of the nodules had disappeared, while the liver contours had become more regular. To our knowledge, the regression of large hypervascular nodules has not previously been reported in patients with Wilson's disease.http://dx.doi.org/10.1155/2009/597371
spellingShingle Alcindo Pissaia
Hervé Gouya
Olivier Scatton
Filoména Conti
Yvon Calmus
Regression of Hypervascular Nodules in a Patient with Wilson's Disease Awaiting Liver Transplantation
Journal of Transplantation
title Regression of Hypervascular Nodules in a Patient with Wilson's Disease Awaiting Liver Transplantation
title_full Regression of Hypervascular Nodules in a Patient with Wilson's Disease Awaiting Liver Transplantation
title_fullStr Regression of Hypervascular Nodules in a Patient with Wilson's Disease Awaiting Liver Transplantation
title_full_unstemmed Regression of Hypervascular Nodules in a Patient with Wilson's Disease Awaiting Liver Transplantation
title_short Regression of Hypervascular Nodules in a Patient with Wilson's Disease Awaiting Liver Transplantation
title_sort regression of hypervascular nodules in a patient with wilson s disease awaiting liver transplantation
url http://dx.doi.org/10.1155/2009/597371
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AT olivierscatton regressionofhypervascularnodulesinapatientwithwilsonsdiseaseawaitinglivertransplantation
AT filomenaconti regressionofhypervascularnodulesinapatientwithwilsonsdiseaseawaitinglivertransplantation
AT yvoncalmus regressionofhypervascularnodulesinapatientwithwilsonsdiseaseawaitinglivertransplantation