Survival and Prognosis for Patients with Rectal Melanomas in the United States: A SEER-Based Study
Purpose Limited attention was paid to focus on rectal melanomas (RM). This study aimed to evaluate the survival rate and prognostic factors of RM.Methods The data for patients with RM from Surveillance, Epidemiology, and End Results (SEER) database were used to analyze tumor survival. Kaplan-Meier m...
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2024-01-01
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| Series: | Journal of Investigative Surgery |
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| Online Access: | https://www.tandfonline.com/doi/10.1080/08941939.2024.2302564 |
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| author | Fan Zhang Boqi Xu Yao Peng Runda Wu Shan Tong Zhongqi Mao |
| author_facet | Fan Zhang Boqi Xu Yao Peng Runda Wu Shan Tong Zhongqi Mao |
| author_sort | Fan Zhang |
| collection | DOAJ |
| description | Purpose Limited attention was paid to focus on rectal melanomas (RM). This study aimed to evaluate the survival rate and prognostic factors of RM.Methods The data for patients with RM from Surveillance, Epidemiology, and End Results (SEER) database were used to analyze tumor survival. Kaplan-Meier method and log-rank test were employed to estimate cancer-specific survival (CSS) and overall survival (OS). A nomogram was established based on the risk factors of survival by the forest plot for multivariate Cox regression analysis. Receiver operating characteristic (ROC) and calibration curve were conducted for validation.Results A total of 187 patients with RM were selected to perform survival analyses. The median survival time of OS was 12 months (range: 0-146 months), and the median survival time of CSS was 12 months (range: 0-74 months). Patients’ age, tumor size, stage, the number of nodes examined, surgery, and radiation were identified as prognostic indicators for CSS by the forest plot for multivariate Cox regression analysis. The nomogram was validated as a reliable model for CSS.Conclusion Clinicopathologic relevance with tumor prognosis was confirmed in this study. Our nomogram can provide a relatively accurate prediction of the survival rate of patients with RM. |
| format | Article |
| id | doaj-art-8bcc221dc3284be0a279e4cb7d347aae |
| institution | OA Journals |
| issn | 0894-1939 1521-0553 |
| language | English |
| publishDate | 2024-01-01 |
| publisher | Taylor & Francis Group |
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| series | Journal of Investigative Surgery |
| spelling | doaj-art-8bcc221dc3284be0a279e4cb7d347aae2025-08-20T02:32:27ZengTaylor & Francis GroupJournal of Investigative Surgery0894-19391521-05532024-01-0137110.1080/08941939.2024.2302564Survival and Prognosis for Patients with Rectal Melanomas in the United States: A SEER-Based StudyFan Zhang0Boqi Xu1Yao Peng2Runda Wu3Shan Tong4Zhongqi Mao5Department of General Surgery, The First Affiliated Hospital of Soochow University, Suzhou, ChinaDepartment of General Surgery, The First Affiliated Hospital of Soochow University, Suzhou, ChinaDepartment of General Surgery, The First Affiliated Hospital of Soochow University, Suzhou, ChinaDepartment of General Surgery, The First Affiliated Hospital of Soochow University, Suzhou, ChinaDepartment of General Surgery, The First Affiliated Hospital of Soochow University, Suzhou, ChinaDepartment of General Surgery, The First Affiliated Hospital of Soochow University, Suzhou, ChinaPurpose Limited attention was paid to focus on rectal melanomas (RM). This study aimed to evaluate the survival rate and prognostic factors of RM.Methods The data for patients with RM from Surveillance, Epidemiology, and End Results (SEER) database were used to analyze tumor survival. Kaplan-Meier method and log-rank test were employed to estimate cancer-specific survival (CSS) and overall survival (OS). A nomogram was established based on the risk factors of survival by the forest plot for multivariate Cox regression analysis. Receiver operating characteristic (ROC) and calibration curve were conducted for validation.Results A total of 187 patients with RM were selected to perform survival analyses. The median survival time of OS was 12 months (range: 0-146 months), and the median survival time of CSS was 12 months (range: 0-74 months). Patients’ age, tumor size, stage, the number of nodes examined, surgery, and radiation were identified as prognostic indicators for CSS by the forest plot for multivariate Cox regression analysis. The nomogram was validated as a reliable model for CSS.Conclusion Clinicopathologic relevance with tumor prognosis was confirmed in this study. Our nomogram can provide a relatively accurate prediction of the survival rate of patients with RM.https://www.tandfonline.com/doi/10.1080/08941939.2024.2302564rectal melanomassurvivalprognosisnomogramSEER |
| spellingShingle | Fan Zhang Boqi Xu Yao Peng Runda Wu Shan Tong Zhongqi Mao Survival and Prognosis for Patients with Rectal Melanomas in the United States: A SEER-Based Study Journal of Investigative Surgery rectal melanomas survival prognosis nomogram SEER |
| title | Survival and Prognosis for Patients with Rectal Melanomas in the United States: A SEER-Based Study |
| title_full | Survival and Prognosis for Patients with Rectal Melanomas in the United States: A SEER-Based Study |
| title_fullStr | Survival and Prognosis for Patients with Rectal Melanomas in the United States: A SEER-Based Study |
| title_full_unstemmed | Survival and Prognosis for Patients with Rectal Melanomas in the United States: A SEER-Based Study |
| title_short | Survival and Prognosis for Patients with Rectal Melanomas in the United States: A SEER-Based Study |
| title_sort | survival and prognosis for patients with rectal melanomas in the united states a seer based study |
| topic | rectal melanomas survival prognosis nomogram SEER |
| url | https://www.tandfonline.com/doi/10.1080/08941939.2024.2302564 |
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