Biomaterials Used for Periodontal Disease Treatment: Focusing on Immunomodulatory Properties

The growing use of biomaterials with different therapeutic purposes increases the need for their physiological understanding as well as to seek its integration with the human body. Chronic inflammatory local pathologies, generally associated with infectious or autoimmunity processes, have been a cur...

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Main Authors: H. Garzón, L. J. Suárez, S. Muñoz, J. Cardona, M. Fontalvo, C. A. Alfonso-Rodríguez
Format: Article
Language:English
Published: Wiley 2022-01-01
Series:International Journal of Biomaterials
Online Access:http://dx.doi.org/10.1155/2022/7693793
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author H. Garzón
L. J. Suárez
S. Muñoz
J. Cardona
M. Fontalvo
C. A. Alfonso-Rodríguez
author_facet H. Garzón
L. J. Suárez
S. Muñoz
J. Cardona
M. Fontalvo
C. A. Alfonso-Rodríguez
author_sort H. Garzón
collection DOAJ
description The growing use of biomaterials with different therapeutic purposes increases the need for their physiological understanding as well as to seek its integration with the human body. Chronic inflammatory local pathologies, generally associated with infectious or autoimmunity processes, have been a current therapeutic target due to the difficulty in their treatment. The recent development of biomaterials with immunomodulatory capacity would then become one of the possible strategies for their management in local pathologies, by intervening in situ, without generating alterations in the systemic immune response. The treatment of periodontal disease as an inflammatory entity has involved the use of different approaches and biomaterials. There is no conclusive, high evidence about the use of these biomaterials in the regeneration of periodontitis sequelae, so the profession keeps looking for other different strategies. The use of biomaterials with immunomodulatory properties could be one, with a promising future. This review of the literature summarizes the scientific evidence about biomaterials used in the treatment of periodontal disease.
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spelling doaj-art-8bc0bef65d9f4f8e891b3e1a87248dc52025-08-20T02:09:14ZengWileyInternational Journal of Biomaterials1687-87952022-01-01202210.1155/2022/7693793Biomaterials Used for Periodontal Disease Treatment: Focusing on Immunomodulatory PropertiesH. Garzón0L. J. Suárez1S. Muñoz2J. Cardona3M. Fontalvo4C. A. Alfonso-Rodríguez5Grupo de Investigación en Salud OralDepartamento de Ciencias Básicas y Medicina OralGrupo de Investigación en Salud OralGrupo de Investigación en Salud OralGrupo de Investigación en Salud OralGrupo de Investigación en Salud OralThe growing use of biomaterials with different therapeutic purposes increases the need for their physiological understanding as well as to seek its integration with the human body. Chronic inflammatory local pathologies, generally associated with infectious or autoimmunity processes, have been a current therapeutic target due to the difficulty in their treatment. The recent development of biomaterials with immunomodulatory capacity would then become one of the possible strategies for their management in local pathologies, by intervening in situ, without generating alterations in the systemic immune response. The treatment of periodontal disease as an inflammatory entity has involved the use of different approaches and biomaterials. There is no conclusive, high evidence about the use of these biomaterials in the regeneration of periodontitis sequelae, so the profession keeps looking for other different strategies. The use of biomaterials with immunomodulatory properties could be one, with a promising future. This review of the literature summarizes the scientific evidence about biomaterials used in the treatment of periodontal disease.http://dx.doi.org/10.1155/2022/7693793
spellingShingle H. Garzón
L. J. Suárez
S. Muñoz
J. Cardona
M. Fontalvo
C. A. Alfonso-Rodríguez
Biomaterials Used for Periodontal Disease Treatment: Focusing on Immunomodulatory Properties
International Journal of Biomaterials
title Biomaterials Used for Periodontal Disease Treatment: Focusing on Immunomodulatory Properties
title_full Biomaterials Used for Periodontal Disease Treatment: Focusing on Immunomodulatory Properties
title_fullStr Biomaterials Used for Periodontal Disease Treatment: Focusing on Immunomodulatory Properties
title_full_unstemmed Biomaterials Used for Periodontal Disease Treatment: Focusing on Immunomodulatory Properties
title_short Biomaterials Used for Periodontal Disease Treatment: Focusing on Immunomodulatory Properties
title_sort biomaterials used for periodontal disease treatment focusing on immunomodulatory properties
url http://dx.doi.org/10.1155/2022/7693793
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AT smunoz biomaterialsusedforperiodontaldiseasetreatmentfocusingonimmunomodulatoryproperties
AT jcardona biomaterialsusedforperiodontaldiseasetreatmentfocusingonimmunomodulatoryproperties
AT mfontalvo biomaterialsusedforperiodontaldiseasetreatmentfocusingonimmunomodulatoryproperties
AT caalfonsorodriguez biomaterialsusedforperiodontaldiseasetreatmentfocusingonimmunomodulatoryproperties