Formulation and Evaluation of Hydrogel Incorporated with Biophytum sensitivum Extract

Background Biophytum sensitivum Linn. represents a promising natural source for the development of hydrogels with potential biomedical applications leveraging its rich medicinal properties for therapeutic benefits in wound healing dermatology and beyond.AimsObjectives In this st...

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Main Authors: Ranit Bandyopadhyay, Ashly Merin George, Selvakumar K, Pratiti Sanyal, Pabitra Samanta, Madhu Kumari, Sourav Nath
Format: Article
Language:English
Published: Rajiv Gandhi University of Health Sciences 2025-01-01
Series:RGUHS Journal of Pharmaceutical Sciences
Online Access:https://journalgrid.com/view/article/rjps/12434444
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author Ranit Bandyopadhyay
Ashly Merin George
Selvakumar K
Pratiti Sanyal
Pabitra Samanta
Madhu Kumari
Sourav Nath
author_facet Ranit Bandyopadhyay
Ashly Merin George
Selvakumar K
Pratiti Sanyal
Pabitra Samanta
Madhu Kumari
Sourav Nath
author_sort Ranit Bandyopadhyay
collection DOAJ
description Background Biophytum sensitivum Linn. represents a promising natural source for the development of hydrogels with potential biomedical applications leveraging its rich medicinal properties for therapeutic benefits in wound healing dermatology and beyond.AimsObjectives In this study Biophytum sensitivum Linn. extract was incorporated into the hydrogel formulation.Methods The formulated hydrogels were evaluated for the appearance homogeneity texture spreadability pH viscosity and extrudability.Results The optimised formulation demonstrated good antimicrobial activity compared to the standard Azithromycin solution. Stability studies conducted at 40plusmn2 RH 75plusmn5 for two months showed no significant degradation of product.Conclusion These findings support the formulation of Biophytum sensitivum Linn. incorporated hydrogel highlighting its strong potential as an antibacterial agent. When delivered in hydrogel form it may offer enhanced therapeutic benefits for the treatment of common skin conditions infections wounds ulcers injuries and diabetes related complications.
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institution Kabale University
issn 2249-2208
language English
publishDate 2025-01-01
publisher Rajiv Gandhi University of Health Sciences
record_format Article
series RGUHS Journal of Pharmaceutical Sciences
spelling doaj-art-8bbebe8970004bef98e5b3258c0f9a2b2025-08-20T03:29:14ZengRajiv Gandhi University of Health SciencesRGUHS Journal of Pharmaceutical Sciences2249-22082025-01-0115210.26463/rjps.15_2_5Formulation and Evaluation of Hydrogel Incorporated with Biophytum sensitivum ExtractRanit BandyopadhyayAshly Merin GeorgeSelvakumar KPratiti SanyalPabitra SamantaMadhu KumariSourav Nath Background Biophytum sensitivum Linn. represents a promising natural source for the development of hydrogels with potential biomedical applications leveraging its rich medicinal properties for therapeutic benefits in wound healing dermatology and beyond.AimsObjectives In this study Biophytum sensitivum Linn. extract was incorporated into the hydrogel formulation.Methods The formulated hydrogels were evaluated for the appearance homogeneity texture spreadability pH viscosity and extrudability.Results The optimised formulation demonstrated good antimicrobial activity compared to the standard Azithromycin solution. Stability studies conducted at 40plusmn2 RH 75plusmn5 for two months showed no significant degradation of product.Conclusion These findings support the formulation of Biophytum sensitivum Linn. incorporated hydrogel highlighting its strong potential as an antibacterial agent. When delivered in hydrogel form it may offer enhanced therapeutic benefits for the treatment of common skin conditions infections wounds ulcers injuries and diabetes related complications.https://journalgrid.com/view/article/rjps/12434444
spellingShingle Ranit Bandyopadhyay
Ashly Merin George
Selvakumar K
Pratiti Sanyal
Pabitra Samanta
Madhu Kumari
Sourav Nath
Formulation and Evaluation of Hydrogel Incorporated with Biophytum sensitivum Extract
RGUHS Journal of Pharmaceutical Sciences
title Formulation and Evaluation of Hydrogel Incorporated with Biophytum sensitivum Extract
title_full Formulation and Evaluation of Hydrogel Incorporated with Biophytum sensitivum Extract
title_fullStr Formulation and Evaluation of Hydrogel Incorporated with Biophytum sensitivum Extract
title_full_unstemmed Formulation and Evaluation of Hydrogel Incorporated with Biophytum sensitivum Extract
title_short Formulation and Evaluation of Hydrogel Incorporated with Biophytum sensitivum Extract
title_sort formulation and evaluation of hydrogel incorporated with biophytum sensitivum extract
url https://journalgrid.com/view/article/rjps/12434444
work_keys_str_mv AT ranitbandyopadhyay formulationandevaluationofhydrogelincorporatedwithbiophytumsensitivumextract
AT ashlymeringeorge formulationandevaluationofhydrogelincorporatedwithbiophytumsensitivumextract
AT selvakumark formulationandevaluationofhydrogelincorporatedwithbiophytumsensitivumextract
AT pratitisanyal formulationandevaluationofhydrogelincorporatedwithbiophytumsensitivumextract
AT pabitrasamanta formulationandevaluationofhydrogelincorporatedwithbiophytumsensitivumextract
AT madhukumari formulationandevaluationofhydrogelincorporatedwithbiophytumsensitivumextract
AT souravnath formulationandevaluationofhydrogelincorporatedwithbiophytumsensitivumextract