Polymyalgia Rheumatica Post-SARS-CoV-2 Infection
There is growing evidence that infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can lead to dysregulation of the immune system and, consequently, the development of autoimmune phenomena. Here, we describe the case of a 75-year-old woman with rheumatic manifestations charac...
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| Format: | Article |
| Language: | English |
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Wiley
2024-01-01
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| Series: | Case Reports in Immunology |
| Online Access: | http://dx.doi.org/10.1155/2024/6662652 |
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| author | Carolina Duarte-Salazar José Eugenio Vazquez-Meraz Lucio Ventura-Ríos Cristina Hernández-Díaz José Arellano-Galindo |
| author_facet | Carolina Duarte-Salazar José Eugenio Vazquez-Meraz Lucio Ventura-Ríos Cristina Hernández-Díaz José Arellano-Galindo |
| author_sort | Carolina Duarte-Salazar |
| collection | DOAJ |
| description | There is growing evidence that infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can lead to dysregulation of the immune system and, consequently, the development of autoimmune phenomena. Here, we describe the case of a 75-year-old woman with rheumatic manifestations characterized by intense musculoskeletal pain and stiffness in the neck and shoulders, with sudden onset and with the inability to raise her arms. The patient was admitted with severe pain located in the neck and shoulders. Previously, she had oropharyngeal pain, severe fatigue, and fever; a real-time polymerase chain reaction test for COVID-19 was positive. Two weeks later, the patient presented localized musculoskeletal pain in the neck and shoulders. Relevant laboratory results included an erythrocyte sedimentation rate of 46 mm/hr and a negative rheumatoid factor test; ultrasound findings with bilateral subacromial–subdeltoid bursitis were observed. A diagnosis of polymyalgia rheumatica (PMR) was initially made according to the EULAR/ACR provisional classification criteria for PMR; however, due to C-reactive protein negativity, the diagnosis was established based on symptoms. Management was with prednisone at the dose of 25 mg/day for 4 weeks and progressive reduction until prednisone suspension. The patient showed complete recovery at 6 months of follow-up. In this case, COVID-19 was implicated in the development of autoimmune and inflammatory rheumatic manifestations. PMR is a rare rheumatic condition that should be included in the wide range of rheumatologic manifestations expressed post-SARS-CoV-2 infection. |
| format | Article |
| id | doaj-art-8bbc0c8db2ef41279e071f7ac5e56ab8 |
| institution | Kabale University |
| issn | 2090-6617 |
| language | English |
| publishDate | 2024-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Immunology |
| spelling | doaj-art-8bbc0c8db2ef41279e071f7ac5e56ab82025-08-20T03:37:41ZengWileyCase Reports in Immunology2090-66172024-01-01202410.1155/2024/6662652Polymyalgia Rheumatica Post-SARS-CoV-2 InfectionCarolina Duarte-Salazar0José Eugenio Vazquez-Meraz1Lucio Ventura-Ríos2Cristina Hernández-Díaz3José Arellano-Galindo4Departmento de ReumatologíaDepartamento de HematologíaDepartmento de ReumatologíaDepartmento de ReumatologíaLaboratorio de Virología Clínica y ExperimentalThere is growing evidence that infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can lead to dysregulation of the immune system and, consequently, the development of autoimmune phenomena. Here, we describe the case of a 75-year-old woman with rheumatic manifestations characterized by intense musculoskeletal pain and stiffness in the neck and shoulders, with sudden onset and with the inability to raise her arms. The patient was admitted with severe pain located in the neck and shoulders. Previously, she had oropharyngeal pain, severe fatigue, and fever; a real-time polymerase chain reaction test for COVID-19 was positive. Two weeks later, the patient presented localized musculoskeletal pain in the neck and shoulders. Relevant laboratory results included an erythrocyte sedimentation rate of 46 mm/hr and a negative rheumatoid factor test; ultrasound findings with bilateral subacromial–subdeltoid bursitis were observed. A diagnosis of polymyalgia rheumatica (PMR) was initially made according to the EULAR/ACR provisional classification criteria for PMR; however, due to C-reactive protein negativity, the diagnosis was established based on symptoms. Management was with prednisone at the dose of 25 mg/day for 4 weeks and progressive reduction until prednisone suspension. The patient showed complete recovery at 6 months of follow-up. In this case, COVID-19 was implicated in the development of autoimmune and inflammatory rheumatic manifestations. PMR is a rare rheumatic condition that should be included in the wide range of rheumatologic manifestations expressed post-SARS-CoV-2 infection.http://dx.doi.org/10.1155/2024/6662652 |
| spellingShingle | Carolina Duarte-Salazar José Eugenio Vazquez-Meraz Lucio Ventura-Ríos Cristina Hernández-Díaz José Arellano-Galindo Polymyalgia Rheumatica Post-SARS-CoV-2 Infection Case Reports in Immunology |
| title | Polymyalgia Rheumatica Post-SARS-CoV-2 Infection |
| title_full | Polymyalgia Rheumatica Post-SARS-CoV-2 Infection |
| title_fullStr | Polymyalgia Rheumatica Post-SARS-CoV-2 Infection |
| title_full_unstemmed | Polymyalgia Rheumatica Post-SARS-CoV-2 Infection |
| title_short | Polymyalgia Rheumatica Post-SARS-CoV-2 Infection |
| title_sort | polymyalgia rheumatica post sars cov 2 infection |
| url | http://dx.doi.org/10.1155/2024/6662652 |
| work_keys_str_mv | AT carolinaduartesalazar polymyalgiarheumaticapostsarscov2infection AT joseeugeniovazquezmeraz polymyalgiarheumaticapostsarscov2infection AT lucioventurarios polymyalgiarheumaticapostsarscov2infection AT cristinahernandezdiaz polymyalgiarheumaticapostsarscov2infection AT josearellanogalindo polymyalgiarheumaticapostsarscov2infection |