CAR T-cell therapies for T-cell malignancies: does cellular immunotherapy represent the best chance of cure?

Abstract: Chimeric antigen receptor T-cell (CAR-T) therapy has proven successful for B-cell lymphomas and leukemias. This success has inspired the development of CAR-T for T-cell malignancies. T-cell lymphomas and T-cell acute lymphoblastic leukemia (T-ALL) are highly heterogenous diseases but are u...

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Bibliographic Details
Main Authors: Nicola Maciocia, Brandon Wade, Paul Maciocia
Format: Article
Language:English
Published: Elsevier 2025-02-01
Series:Blood Advances
Online Access:http://www.sciencedirect.com/science/article/pii/S2473952924007432
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