Epidemiologic study of chronic kidney disease in diabetes mellitus of Chengdu railway worker
Objective To identify the prevalence and related risk factors of chronic kidney disease（CKD） in diabetes mellitus of Chengdu railway worker.Methods 967 eligible samples of railway workers with diabetes mellitus,taken from Sep.2009 to Dec.2013 " Health examination data of Chengdu urban groups&qu...
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Editorial Department of Journal of Clinical Nephrology
2016-01-01
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| Series: | Linchuang shenzangbing zazhi |
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| author | GUO Zong-lin QIAN Quan FU Bin WANG Qi-rong GAO Xiang LIANG Jiang-hong PU Li-jun SU Xiao-yu |
| author_facet | GUO Zong-lin QIAN Quan FU Bin WANG Qi-rong GAO Xiang LIANG Jiang-hong PU Li-jun SU Xiao-yu |
| author_sort | GUO Zong-lin |
| collection | DOAJ |
| description | Objective To identify the prevalence and related risk factors of chronic kidney disease（CKD） in diabetes mellitus of Chengdu railway worker.Methods 967 eligible samples of railway workers with diabetes mellitus,taken from Sep.2009 to Dec.2013 " Health examination data of Chengdu urban groups" were selected.The data included questionnaire（sex,age,smoking,drinking and anamnesis）,somatoscopy（blood pressure,body height and body weight）,blood and urine examination indicators（urea nitrogen,blood creatinine,blood uric acid,blood glucose,cholesterol,triglyceride,urine microalbumin/urine creatinine ratio and routine urine examination）.According to the CKD criteria:albuminuria（urine microalbumin/urine creatinine ratio ≥30 mg/g）,hematuria（erythrocytes >3/HP in urinary sediment） and reduced estimated glomerular filtration rate[eGFR <60 ml·min<sup>-1</sup>·（1.73 m<sup>2</sup>）<sup>-1</sup>],the data were analyzed.Results（1）Prevalence of albuminuria,hematuria,reduced eGFR and CKD in the diabetes mellitus group was 28.02%,1.45%,13.75%and 37.64%respectively.Prevalence of albuminuria in the diabetes mellitus group was obviously higher than in the non-diabetes mellitus group or prediabetic state group.Prevalence of albuminuria,reduced eGFR and CKD in the group of diabetes mellitus complicated with hypertension and hyperuricemia and hyperlipidemia was obviously higher than in simple diabetes mellitus group.（2） Fasting blood glucose level had a positively linear correlation with urine microalbumin/urine creatinine.（3） Age,body mass index（BMI）,hypertension and fasting blood glucose level were independent risk factors of albuminuria.Female was independent risk factor of hematuria.Hyperuricemia and fasting blood glucose level were independent risk factors of reduced eGFR.Age,BMI,hypertension,hyperuricemia and fasting blood glucose level were independent risk factors of CKD.Conclusions The prevalence of CKD was higher than ordinary people in diabetes mellitus group of Chengdu railway worker and is related with fasting blood glucose level.Control of blood glucose,blood pressure,blood uric acid,blood fat and BMI helps reducing the occurrence and development of CKD. |
| format | Article |
| id | doaj-art-8bab3e5da33f4493a227b7919c5613fa |
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| issn | 1671-2390 |
| language | zho |
| publishDate | 2016-01-01 |
| publisher | Editorial Department of Journal of Clinical Nephrology |
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| series | Linchuang shenzangbing zazhi |
| spelling | doaj-art-8bab3e5da33f4493a227b7919c5613fa2025-08-20T01:51:10ZzhoEditorial Department of Journal of Clinical NephrologyLinchuang shenzangbing zazhi1671-23902016-01-0173473857919349Epidemiologic study of chronic kidney disease in diabetes mellitus of Chengdu railway workerGUO Zong-linQIAN QuanFU BinWANG Qi-rongGAO XiangLIANG Jiang-hongPU Li-junSU Xiao-yuObjective To identify the prevalence and related risk factors of chronic kidney disease（CKD） in diabetes mellitus of Chengdu railway worker.Methods 967 eligible samples of railway workers with diabetes mellitus,taken from Sep.2009 to Dec.2013 " Health examination data of Chengdu urban groups" were selected.The data included questionnaire（sex,age,smoking,drinking and anamnesis）,somatoscopy（blood pressure,body height and body weight）,blood and urine examination indicators（urea nitrogen,blood creatinine,blood uric acid,blood glucose,cholesterol,triglyceride,urine microalbumin/urine creatinine ratio and routine urine examination）.According to the CKD criteria:albuminuria（urine microalbumin/urine creatinine ratio ≥30 mg/g）,hematuria（erythrocytes >3/HP in urinary sediment） and reduced estimated glomerular filtration rate[eGFR <60 ml·min<sup>-1</sup>·（1.73 m<sup>2</sup>）<sup>-1</sup>],the data were analyzed.Results（1）Prevalence of albuminuria,hematuria,reduced eGFR and CKD in the diabetes mellitus group was 28.02%,1.45%,13.75%and 37.64%respectively.Prevalence of albuminuria in the diabetes mellitus group was obviously higher than in the non-diabetes mellitus group or prediabetic state group.Prevalence of albuminuria,reduced eGFR and CKD in the group of diabetes mellitus complicated with hypertension and hyperuricemia and hyperlipidemia was obviously higher than in simple diabetes mellitus group.（2） Fasting blood glucose level had a positively linear correlation with urine microalbumin/urine creatinine.（3） Age,body mass index（BMI）,hypertension and fasting blood glucose level were independent risk factors of albuminuria.Female was independent risk factor of hematuria.Hyperuricemia and fasting blood glucose level were independent risk factors of reduced eGFR.Age,BMI,hypertension,hyperuricemia and fasting blood glucose level were independent risk factors of CKD.Conclusions The prevalence of CKD was higher than ordinary people in diabetes mellitus group of Chengdu railway worker and is related with fasting blood glucose level.Control of blood glucose,blood pressure,blood uric acid,blood fat and BMI helps reducing the occurrence and development of CKD.http://www.lcszb.com/thesisDetails?columnId=57919349&Fpath=home&index=0DiabetesChronic kidney diseaseRisk factors |
| spellingShingle | GUO Zong-lin QIAN Quan FU Bin WANG Qi-rong GAO Xiang LIANG Jiang-hong PU Li-jun SU Xiao-yu Epidemiologic study of chronic kidney disease in diabetes mellitus of Chengdu railway worker Linchuang shenzangbing zazhi Diabetes Chronic kidney disease Risk factors |
| title | Epidemiologic study of chronic kidney disease in diabetes mellitus of Chengdu railway worker |
| title_full | Epidemiologic study of chronic kidney disease in diabetes mellitus of Chengdu railway worker |
| title_fullStr | Epidemiologic study of chronic kidney disease in diabetes mellitus of Chengdu railway worker |
| title_full_unstemmed | Epidemiologic study of chronic kidney disease in diabetes mellitus of Chengdu railway worker |
| title_short | Epidemiologic study of chronic kidney disease in diabetes mellitus of Chengdu railway worker |
| title_sort | epidemiologic study of chronic kidney disease in diabetes mellitus of chengdu railway worker |
| topic | Diabetes Chronic kidney disease Risk factors |
| url | http://www.lcszb.com/thesisDetails?columnId=57919349&Fpath=home&index=0 |
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