Effects of discontinuing different antiresorptive regimens on medication-related osteonecrosis of the jaw in patients undergoing dental procedures: a systematic review and network meta-analysis

Effects of discontinuing different antiresorptive regimens on medication-related osteonecrosis of the jaw in patients undergoing dental procedures: a systematic review and network meta-analysis

Purpose: Controversy exists on whether a drug holiday is necessary for patients on antiresorptive medication for osteoporosis or bone metastasis and undergoing dental procedures to lower the risk of medication-related osteonecrosis of the jaw (MRONJ). This study evaluated the effects of discontinuin...

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Bibliographic Details
Main Authors: Kasidid Ruksakiet, Atthakorn Jarusriwanna, Wuttapon Sadaeng, Artit Laoruengthana, Thanyaporn Sang-Ngoen, Teerapon Dhippayom
Format: Article
Language:English
Published: Bioscientifica 2025-05-01
Series:EFORT Open Reviews
Subjects:
antiresorptives
bisphosphonates
denosumab
osteonecrosis of the jaw
osteoporosis
bone metastasis
Online Access:https://eor.bioscientifica.com/view/journals/eor/10/5/EOR-2024-0133.xml
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