Extracellular vesicles in TDP-43 proteinopathies: pathogenesis and biomarker potential

Extracellular vesicles in TDP-43 proteinopathies: pathogenesis and biomarker potential

Abstract Extracellular vesicles (EVs) are membrane-enclosed nanoparticles released by most cell types, and from multiple sub-cellular compartments. They carry a range of cargo biomolecules, including protein and RNA that reflect the type and status of their cell of origin. EVs are associated with th...

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Bibliographic Details
Main Authors: Elizabeth R. Dellar, Lara Nikel, Stephanie Fowler, Björn F. Vahsen, Ruxandra Dafinca, Emily Feneberg, Kevin Talbot, Martin R. Turner, Alexander G. Thompson
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Molecular Neurodegeneration
Online Access:https://doi.org/10.1186/s13024-025-00859-4
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