Manifestations of the oral mucosa and salivary glands in irritable bowel syndrome and microscopic colitis – A systematic review

Objective: There is a well-established association of oral manifestations in the non-infectious chronic diarrhoeal conditions namely, Morbus Crohn, ulcerative colitis, and coeliac disease. Such a connection may exist also for the remaining non-infectious chronic diarrhoeal conditions, that is irrit...

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Main Authors: Hanna Göthlin, Bengt Hasséus, Klas Sjöberg, Maria Bankvall
Format: Article
Language:English
Published: Medical Journals Sweden 2025-06-01
Series:Acta Odontologica Scandinavica
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Online Access:https://medicaljournalssweden.se/actaodontologica/article/view/43870
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author Hanna Göthlin
Bengt Hasséus
Klas Sjöberg
Maria Bankvall
author_facet Hanna Göthlin
Bengt Hasséus
Klas Sjöberg
Maria Bankvall
author_sort Hanna Göthlin
collection DOAJ
description Objective: There is a well-established association of oral manifestations in the non-infectious chronic diarrhoeal conditions namely, Morbus Crohn, ulcerative colitis, and coeliac disease. Such a connection may exist also for the remaining non-infectious chronic diarrhoeal conditions, that is irritable bowel syndrome (IBS) and microscopic colitis (MC). Materials and methods: A systematic search was performed in Scopus and PubMed, rendering a total of 710 articles to be screened. All articles were screened independently and assessed for eligibility reporting comorbidity between either IBS or MC, and oral symptoms/disease. Quality assessment and data extraction were performed. Results: In all, 17 articles were included. Sjögren’s syndrome (SS) in patients with IBS ranged from 3% to 33% and for IBS in SS between 29% to 62%. Dry mouth, bad breath, and foul taste were overrepresented in these patients. The occurrence of SS in patients with MC ranged from 2% to 9%, and for MC in SS from 1% to 2%. Conclusions: An association between SS and IBS and MC, respectively, is plausible. Few articles have explored other oral manifestations. Therefore, no specific conclusions can be drawn. It is pivotal to further explore oral manifestations of these conditions bridging the gap between dental care and general medicine to optimise diagnostics, treatment strategies, and ultimately patient care.
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spelling doaj-art-8b9dfd5f67fb40f1b0897bc66d1fb20f2025-08-20T03:10:46ZengMedical Journals SwedenActa Odontologica Scandinavica0001-63571502-38502025-06-018410.2340/aos.v84.43870Manifestations of the oral mucosa and salivary glands in irritable bowel syndrome and microscopic colitis – A systematic reviewHanna Göthlin0Bengt Hasséus1Klas Sjöberg2Maria Bankvall3Department of Oral Medicine & Pathology, Institute of Odontology, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, SwedenDepartment of Oral Medicine & Pathology, Institute of Odontology, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, SwedenDepartment of Clinical Sciences, Malmö, Lund University, Malmö, Sweden; Department of Gastroenterology and Nutrition, Skåne University Hospital, Malmö, SwedenDepartment of Dental Medicine, Karolinska Institute, Huddinge, Sweden; Department of Odontology and Oral Sciences, School of Health and Welfare, University of Jönköping, Sweden Objective: There is a well-established association of oral manifestations in the non-infectious chronic diarrhoeal conditions namely, Morbus Crohn, ulcerative colitis, and coeliac disease. Such a connection may exist also for the remaining non-infectious chronic diarrhoeal conditions, that is irritable bowel syndrome (IBS) and microscopic colitis (MC). Materials and methods: A systematic search was performed in Scopus and PubMed, rendering a total of 710 articles to be screened. All articles were screened independently and assessed for eligibility reporting comorbidity between either IBS or MC, and oral symptoms/disease. Quality assessment and data extraction were performed. Results: In all, 17 articles were included. Sjögren’s syndrome (SS) in patients with IBS ranged from 3% to 33% and for IBS in SS between 29% to 62%. Dry mouth, bad breath, and foul taste were overrepresented in these patients. The occurrence of SS in patients with MC ranged from 2% to 9%, and for MC in SS from 1% to 2%. Conclusions: An association between SS and IBS and MC, respectively, is plausible. Few articles have explored other oral manifestations. Therefore, no specific conclusions can be drawn. It is pivotal to further explore oral manifestations of these conditions bridging the gap between dental care and general medicine to optimise diagnostics, treatment strategies, and ultimately patient care. https://medicaljournalssweden.se/actaodontologica/article/view/43870Gastrointestinal diseaseirritable bowel syndromemicroscopic colitisoral cavityoral mucosal disease
spellingShingle Hanna Göthlin
Bengt Hasséus
Klas Sjöberg
Maria Bankvall
Manifestations of the oral mucosa and salivary glands in irritable bowel syndrome and microscopic colitis – A systematic review
Acta Odontologica Scandinavica
Gastrointestinal disease
irritable bowel syndrome
microscopic colitis
oral cavity
oral mucosal disease
title Manifestations of the oral mucosa and salivary glands in irritable bowel syndrome and microscopic colitis – A systematic review
title_full Manifestations of the oral mucosa and salivary glands in irritable bowel syndrome and microscopic colitis – A systematic review
title_fullStr Manifestations of the oral mucosa and salivary glands in irritable bowel syndrome and microscopic colitis – A systematic review
title_full_unstemmed Manifestations of the oral mucosa and salivary glands in irritable bowel syndrome and microscopic colitis – A systematic review
title_short Manifestations of the oral mucosa and salivary glands in irritable bowel syndrome and microscopic colitis – A systematic review
title_sort manifestations of the oral mucosa and salivary glands in irritable bowel syndrome and microscopic colitis a systematic review
topic Gastrointestinal disease
irritable bowel syndrome
microscopic colitis
oral cavity
oral mucosal disease
url https://medicaljournalssweden.se/actaodontologica/article/view/43870
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