Excavatolide C has oxidative-stress-dependent antiproliferative and apoptotic effects against breast cancer cells

Excavatolide C has oxidative-stress-dependent antiproliferative and apoptotic effects against breast cancer cells

Abstract Background Triple negative breast cancer (TNBC) shows a poor response to targeted therapy drugs for non-triple-negative breast cancer (non-TNBC). Developing anticancer drugs that are effective for both TNBC and non-TNBC cells is necessary. The marine coral Briareum excavatum-derived excavat...

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Bibliographic Details
Main Authors: Jun-Ping Shiau, Che-Wei Yang, Wangta Liu, Szu-Yin Yu, Chia-Hung Yen, Fang-Rong Chang, Jyh-Horng Sheu, Hsueh-Wei Chang
Format: Article
Language:English
Published: BMC 2025-07-01
Series:BMC Cancer
Subjects:
Soft coral
Diterpenes
Breast cancer
Oxidative stress
Apoptosis
DNA damage
Online Access:https://doi.org/10.1186/s12885-025-14276-9
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