SOME IMMUNE INDICATORS IN PATIENTS WITH AIRWAY OBSTRUCTION AND CONCOMITANT INTESTINAL PARASITOSES
Aim. To study basic immune indicators in patients with respiratory diseases accompanied by airway obstruction and intestinal parasitoses. Materials and Methods. We recruited 36 patients with airway obstruction and helminthiases, 31 patients with airway obstruction and protozoan infections, 30 pa...
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| Main Authors: | , |
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| Format: | Article |
| Language: | Russian |
| Published: |
Kemerovo State Medical University
2018-03-01
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| Series: | Фундаментальная и клиническая медицина |
| Subjects: | |
| Online Access: | https://fcm.kemsmu.ru/jour/article/view/77 |
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| Summary: | Aim. To study basic immune indicators in patients with respiratory diseases accompanied by airway obstruction and intestinal parasitoses. Materials and Methods. We recruited 36 patients with airway obstruction and helminthiases, 31 patients with airway obstruction and protozoan infections, 30 patients with airway obstruction and combined parasitism, and 23 patients with airway obstruction without concomitant parasitoses. We measured the number of CD3+, CD4+, CD8+, and CD16+ cells and calculated CD4/CD8 ratio; in addition, we performed spontaneous and stimulated nitroblue tetrazolium (NBT) test and measured serum levels of IgA, IgM, IgG, IgE, circulating immune complexes, and complement components 3 and 4. Results. Mean values of all lymphocyte parameters were significantly lower while the number of NBT-positive neutrophils was significantly higher in patients with parasitoses compared to those without. Among immunoglobulins, IgM values were significantly lower whereas those for IgG and IgE were significantly higher in patients with airway obstruction and parasitic infections as compared to patients with airway obstruction alone. No considerable intergroup differences in circulatory immune complexes and complement components were revealed. Conclusion. Concomitant parasitoses do not cause severe immune disorders in patients with airway obstruction. |
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| ISSN: | 2500-0764 2542-0941 |