Place of enalapril in treatment of patients with systemic lupus erythematosus and systemic sclerosis
Lupus erythematosus (SLE) and systemic sclerosis (SS). Methods. 45 SLE and 44 SS pts were included. Some of them received antirheumatic drugs in combination with enalapril other were treated with antirheumatic drugs only. The pts were examined before and 6-12 months after the beginning of the treatm...
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| Language: | Russian |
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IMA PRESS LLC
2003-02-01
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| Series: | Научно-практическая ревматология |
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| Online Access: | https://rsp.mediar-press.net/rsp/article/view/1053 |
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| author | L K Kozlova V V Bagirova |
| author_facet | L K Kozlova V V Bagirova |
| author_sort | L K Kozlova |
| collection | DOAJ |
| description | Lupus erythematosus (SLE) and systemic sclerosis (SS). Methods. 45 SLE and 44 SS pts were included. Some of them received antirheumatic drugs in combination with enalapril other were treated with antirheumatic drugs only. The pts were examined before and 6-12 months after the beginning of the treatment. Echocardioscopy and biomicroscopy of bulbar conjunctiva vessels were performed in all cases. Results. Treatment with enalapril improved state of all SLE and SS pts. The drug was well tolerated and provided decrease of dyspnoea and edema as well as blood pressure normalization. Most prominent improvement was evident 12 months after the beginning of enalapril treatment. Reduction of left ventricle myocardium hypertrophy, improvement of its diastolic function and reduction of structural changes of bulbar conjunctiva microcirculation were achieved at that time. Conclusion. Enalapril administration in combination with antirheumatic drugs improves state of SLE and SS pts as well as echocardiography and bulbar conjunctiva vessels biomicroscopy results. It can be recommended for treatment of these diseases. |
| format | Article |
| id | doaj-art-8b7d1a0cae924da78eecc5a78828583d |
| institution | Kabale University |
| issn | 1995-4484 1995-4492 |
| language | Russian |
| publishDate | 2003-02-01 |
| publisher | IMA PRESS LLC |
| record_format | Article |
| series | Научно-практическая ревматология |
| spelling | doaj-art-8b7d1a0cae924da78eecc5a78828583d2025-08-20T03:38:34ZrusIMA PRESS LLCНаучно-практическая ревматология1995-44841995-44922003-02-01411475110.14412/1995-4484-2003-1135993Place of enalapril in treatment of patients with systemic lupus erythematosus and systemic sclerosisL K KozlovaV V BagirovaLupus erythematosus (SLE) and systemic sclerosis (SS). Methods. 45 SLE and 44 SS pts were included. Some of them received antirheumatic drugs in combination with enalapril other were treated with antirheumatic drugs only. The pts were examined before and 6-12 months after the beginning of the treatment. Echocardioscopy and biomicroscopy of bulbar conjunctiva vessels were performed in all cases. Results. Treatment with enalapril improved state of all SLE and SS pts. The drug was well tolerated and provided decrease of dyspnoea and edema as well as blood pressure normalization. Most prominent improvement was evident 12 months after the beginning of enalapril treatment. Reduction of left ventricle myocardium hypertrophy, improvement of its diastolic function and reduction of structural changes of bulbar conjunctiva microcirculation were achieved at that time. Conclusion. Enalapril administration in combination with antirheumatic drugs improves state of SLE and SS pts as well as echocardiography and bulbar conjunctiva vessels biomicroscopy results. It can be recommended for treatment of these diseases.https://rsp.mediar-press.net/rsp/article/view/1053systemic lupus erythematosussystemic sclerosismicrocirculationenalapril |
| spellingShingle | L K Kozlova V V Bagirova Place of enalapril in treatment of patients with systemic lupus erythematosus and systemic sclerosis Научно-практическая ревматология systemic lupus erythematosus systemic sclerosis microcirculation enalapril |
| title | Place of enalapril in treatment of patients with systemic lupus erythematosus and systemic sclerosis |
| title_full | Place of enalapril in treatment of patients with systemic lupus erythematosus and systemic sclerosis |
| title_fullStr | Place of enalapril in treatment of patients with systemic lupus erythematosus and systemic sclerosis |
| title_full_unstemmed | Place of enalapril in treatment of patients with systemic lupus erythematosus and systemic sclerosis |
| title_short | Place of enalapril in treatment of patients with systemic lupus erythematosus and systemic sclerosis |
| title_sort | place of enalapril in treatment of patients with systemic lupus erythematosus and systemic sclerosis |
| topic | systemic lupus erythematosus systemic sclerosis microcirculation enalapril |
| url | https://rsp.mediar-press.net/rsp/article/view/1053 |
| work_keys_str_mv | AT lkkozlova placeofenalaprilintreatmentofpatientswithsystemiclupuserythematosusandsystemicsclerosis AT vvbagirova placeofenalaprilintreatmentofpatientswithsystemiclupuserythematosusandsystemicsclerosis |