Predictability of central corneal stromal thickness reduction in InnovEyes ablation profile: A retrospective study
Objective: To evaluate the predictability of the central corneal stromal thickness (CST) reduction in InnovEyes ablation profile.Methods: The retrospective study included 118 eyes (61 patients) who underwent surgeries based on InnovEyes profile and 117 eyes (67 patients) based on the Custom-Q. The c...
Saved in:
| Main Authors: | , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-06-01
|
| Series: | Photodiagnosis and Photodynamic Therapy |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1572100025000997 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849701402388987904 |
|---|---|
| author | Shimin Tan Yimeng Fan Xindi Wang Yu Zhang Yunpeng Li Xiaojuan Fan Zhao Liu Shengjian Mi Qianyan Kang |
| author_facet | Shimin Tan Yimeng Fan Xindi Wang Yu Zhang Yunpeng Li Xiaojuan Fan Zhao Liu Shengjian Mi Qianyan Kang |
| author_sort | Shimin Tan |
| collection | DOAJ |
| description | Objective: To evaluate the predictability of the central corneal stromal thickness (CST) reduction in InnovEyes ablation profile.Methods: The retrospective study included 118 eyes (61 patients) who underwent surgeries based on InnovEyes profile and 117 eyes (67 patients) based on the Custom-Q. The central CST, the central corneal thickness (CT) and the central corneal epithelial thickness (CET) were measured using anterior segment optical coherence tomography (AS-OCT) preoperatively and postoperatively over 3 months. The planned-achieved thickness (PAD) was calculated. Planned and achieved central CST, PAD and increase of central CET were compared.Results: The achieved central CST reduction was 113.60 ± 21.88 μm in the InnovEyes group, which was not significantly different from the planned (108.70 ± 19.87 μm, P = 0.075). There was a strong correlation between the achieved central CST reduction and the planned reduction in the InnovEyes group (R2 = 0.884, P < 0.001), which was stronger than in the Custom-Q group (R2 = 0.861, P < 0.001). The PAD of central CST reduction was -4.87 ± 8.17 μm and -4.76 ± 9.75 μm for the InnovEyes and Custom-Q groups, respectively (P = 0.966). The increase of central CET was 3.29 ± 3.97 μm in InnovEyes group and 4.39 ± 4.84 μm in Custom-Q group, with no significant difference (P = 0.064).Conclusions: The InnovEyes ablation profile demonstrates good predictability of the central CST reduction, ensuring the safety of this novel profile. Besides, the InnovEyes profile may have taken postoperative corneal epithelial remodeling into consideration, and provided an enhanced pre-compensation. |
| format | Article |
| id | doaj-art-8b6f9cd9b5f5452684ca4acf056eff3d |
| institution | DOAJ |
| issn | 1572-1000 |
| language | English |
| publishDate | 2025-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Photodiagnosis and Photodynamic Therapy |
| spelling | doaj-art-8b6f9cd9b5f5452684ca4acf056eff3d2025-08-20T03:17:57ZengElsevierPhotodiagnosis and Photodynamic Therapy1572-10002025-06-015310457010.1016/j.pdpdt.2025.104570Predictability of central corneal stromal thickness reduction in InnovEyes ablation profile: A retrospective studyShimin Tan0Yimeng Fan1Xindi Wang2Yu Zhang3Yunpeng Li4Xiaojuan Fan5Zhao Liu6Shengjian Mi7Qianyan Kang8Department of Ophthalmology, the First Affiliated Hospital of Xi'an Jiaotong University, 277 West Yanta Road, Xi'an, Shaanxi, 710061, PR ChinaDepartment of Ophthalmology, the First Affiliated Hospital of Xi'an Jiaotong University, 277 West Yanta Road, Xi'an, Shaanxi, 710061, PR ChinaDepartment of Ophthalmology, the First Affiliated Hospital of Xi'an Jiaotong University, 277 West Yanta Road, Xi'an, Shaanxi, 710061, PR ChinaDepartment of Ophthalmology, the First Affiliated Hospital of Xi'an Jiaotong University, 277 West Yanta Road, Xi'an, Shaanxi, 710061, PR ChinaDepartment of Ophthalmology, the First Affiliated Hospital of Xi'an Jiaotong University, 277 West Yanta Road, Xi'an, Shaanxi, 710061, PR ChinaDepartment of Ophthalmology, the First Affiliated Hospital of Xi'an Jiaotong University, 277 West Yanta Road, Xi'an, Shaanxi, 710061, PR ChinaCorrespondence author at. Department of Ophthalmology, the First Affiliated Hospital of Xi'an Jiaotong University, 277 West Yanta Road, Xi'an, Shaanxi, 710061, PR China.; Department of Ophthalmology, the First Affiliated Hospital of Xi'an Jiaotong University, 277 West Yanta Road, Xi'an, Shaanxi, 710061, PR ChinaDepartment of Ophthalmology, the First Affiliated Hospital of Xi'an Jiaotong University, 277 West Yanta Road, Xi'an, Shaanxi, 710061, PR ChinaDepartment of Ophthalmology, the First Affiliated Hospital of Xi'an Jiaotong University, 277 West Yanta Road, Xi'an, Shaanxi, 710061, PR ChinaObjective: To evaluate the predictability of the central corneal stromal thickness (CST) reduction in InnovEyes ablation profile.Methods: The retrospective study included 118 eyes (61 patients) who underwent surgeries based on InnovEyes profile and 117 eyes (67 patients) based on the Custom-Q. The central CST, the central corneal thickness (CT) and the central corneal epithelial thickness (CET) were measured using anterior segment optical coherence tomography (AS-OCT) preoperatively and postoperatively over 3 months. The planned-achieved thickness (PAD) was calculated. Planned and achieved central CST, PAD and increase of central CET were compared.Results: The achieved central CST reduction was 113.60 ± 21.88 μm in the InnovEyes group, which was not significantly different from the planned (108.70 ± 19.87 μm, P = 0.075). There was a strong correlation between the achieved central CST reduction and the planned reduction in the InnovEyes group (R2 = 0.884, P < 0.001), which was stronger than in the Custom-Q group (R2 = 0.861, P < 0.001). The PAD of central CST reduction was -4.87 ± 8.17 μm and -4.76 ± 9.75 μm for the InnovEyes and Custom-Q groups, respectively (P = 0.966). The increase of central CET was 3.29 ± 3.97 μm in InnovEyes group and 4.39 ± 4.84 μm in Custom-Q group, with no significant difference (P = 0.064).Conclusions: The InnovEyes ablation profile demonstrates good predictability of the central CST reduction, ensuring the safety of this novel profile. Besides, the InnovEyes profile may have taken postoperative corneal epithelial remodeling into consideration, and provided an enhanced pre-compensation.http://www.sciencedirect.com/science/article/pii/S1572100025000997InnoveyesOptical ray tracingAblation profilesCorneal stromal thickness (CST)Anterior segment optical coherence tomography (AS‑OCT) |
| spellingShingle | Shimin Tan Yimeng Fan Xindi Wang Yu Zhang Yunpeng Li Xiaojuan Fan Zhao Liu Shengjian Mi Qianyan Kang Predictability of central corneal stromal thickness reduction in InnovEyes ablation profile: A retrospective study Photodiagnosis and Photodynamic Therapy Innoveyes Optical ray tracing Ablation profiles Corneal stromal thickness (CST) Anterior segment optical coherence tomography (AS‑OCT) |
| title | Predictability of central corneal stromal thickness reduction in InnovEyes ablation profile: A retrospective study |
| title_full | Predictability of central corneal stromal thickness reduction in InnovEyes ablation profile: A retrospective study |
| title_fullStr | Predictability of central corneal stromal thickness reduction in InnovEyes ablation profile: A retrospective study |
| title_full_unstemmed | Predictability of central corneal stromal thickness reduction in InnovEyes ablation profile: A retrospective study |
| title_short | Predictability of central corneal stromal thickness reduction in InnovEyes ablation profile: A retrospective study |
| title_sort | predictability of central corneal stromal thickness reduction in innoveyes ablation profile a retrospective study |
| topic | Innoveyes Optical ray tracing Ablation profiles Corneal stromal thickness (CST) Anterior segment optical coherence tomography (AS‑OCT) |
| url | http://www.sciencedirect.com/science/article/pii/S1572100025000997 |
| work_keys_str_mv | AT shimintan predictabilityofcentralcornealstromalthicknessreductionininnoveyesablationprofilearetrospectivestudy AT yimengfan predictabilityofcentralcornealstromalthicknessreductionininnoveyesablationprofilearetrospectivestudy AT xindiwang predictabilityofcentralcornealstromalthicknessreductionininnoveyesablationprofilearetrospectivestudy AT yuzhang predictabilityofcentralcornealstromalthicknessreductionininnoveyesablationprofilearetrospectivestudy AT yunpengli predictabilityofcentralcornealstromalthicknessreductionininnoveyesablationprofilearetrospectivestudy AT xiaojuanfan predictabilityofcentralcornealstromalthicknessreductionininnoveyesablationprofilearetrospectivestudy AT zhaoliu predictabilityofcentralcornealstromalthicknessreductionininnoveyesablationprofilearetrospectivestudy AT shengjianmi predictabilityofcentralcornealstromalthicknessreductionininnoveyesablationprofilearetrospectivestudy AT qianyankang predictabilityofcentralcornealstromalthicknessreductionininnoveyesablationprofilearetrospectivestudy |