What Do We Know About Bacterial Infections in Hidradenitis Suppurativa?—A Narrative Review
<b>Background/Objectives</b>: Hidradenitis suppurativa is an inflammatory skin condition of the pilosebaceous unit of a chronic, painful, and progressive nature. It affects intertriginous parts of the body, including the axillae, groin, submammary region, and anogenital region. The risk...
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MDPI AG
2025-02-01
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| author | Zuzanna Świerczewska Wioletta Barańska-Rybak |
| author_facet | Zuzanna Świerczewska Wioletta Barańska-Rybak |
| author_sort | Zuzanna Świerczewska |
| collection | DOAJ |
| description | <b>Background/Objectives</b>: Hidradenitis suppurativa is an inflammatory skin condition of the pilosebaceous unit of a chronic, painful, and progressive nature. It affects intertriginous parts of the body, including the axillae, groin, submammary region, and anogenital region. The risk of infection in HS patients is not well understood. Thus, presenting the most recent findings in the study of bacterial infections in relation to hidradenitis suppurativa was the objective of this review. <b>Methods</b>: The presented article is a narrative review. The PubMed and Scopus databases were searched for articles applicable to this review. All types of study design were included in this review. <b>Results</b>: Among reported infections in patients with HS, Fournier’s gangrene, osteomyelitis, <i>Clostridium difficile</i> infection, and biofilm were significant. Attention should also be paid to post-procedural infections. <b>Conclusions</b>: A wide range of bacterial infections, from localized purulent infections to serious systemic consequences, can affect patients with HS. Comorbid diseases like diabetes mellitus and obesity change the cutaneous microbiota and produce a pro-inflammatory systemic milieu, which makes the disease more severe and makes HS patients more susceptible to infections. Additionally, those with untreated or unmanaged HS are more likely to experience infectious complications. |
| format | Article |
| id | doaj-art-8b69e46786904efda60bcfffc6d43318 |
| institution | DOAJ |
| issn | 2079-6382 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | MDPI AG |
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| series | Antibiotics |
| spelling | doaj-art-8b69e46786904efda60bcfffc6d433182025-08-20T02:44:55ZengMDPI AGAntibiotics2079-63822025-02-0114214210.3390/antibiotics14020142What Do We Know About Bacterial Infections in Hidradenitis Suppurativa?—A Narrative ReviewZuzanna Świerczewska0Wioletta Barańska-Rybak1Department of Dermatology, Venereology, and Allergology, Faculty of Medicine, Medical University of Gdańsk, Smoluchowskiego 17, 80-214 Gdańsk, PolandDepartment of Dermatology, Venereology, and Allergology, Faculty of Medicine, Medical University of Gdańsk, Smoluchowskiego 17, 80-214 Gdańsk, Poland<b>Background/Objectives</b>: Hidradenitis suppurativa is an inflammatory skin condition of the pilosebaceous unit of a chronic, painful, and progressive nature. It affects intertriginous parts of the body, including the axillae, groin, submammary region, and anogenital region. The risk of infection in HS patients is not well understood. Thus, presenting the most recent findings in the study of bacterial infections in relation to hidradenitis suppurativa was the objective of this review. <b>Methods</b>: The presented article is a narrative review. The PubMed and Scopus databases were searched for articles applicable to this review. All types of study design were included in this review. <b>Results</b>: Among reported infections in patients with HS, Fournier’s gangrene, osteomyelitis, <i>Clostridium difficile</i> infection, and biofilm were significant. Attention should also be paid to post-procedural infections. <b>Conclusions</b>: A wide range of bacterial infections, from localized purulent infections to serious systemic consequences, can affect patients with HS. Comorbid diseases like diabetes mellitus and obesity change the cutaneous microbiota and produce a pro-inflammatory systemic milieu, which makes the disease more severe and makes HS patients more susceptible to infections. Additionally, those with untreated or unmanaged HS are more likely to experience infectious complications.https://www.mdpi.com/2079-6382/14/2/142hidradenitis suppurativaacne inversainfectionsbacteria |
| spellingShingle | Zuzanna Świerczewska Wioletta Barańska-Rybak What Do We Know About Bacterial Infections in Hidradenitis Suppurativa?—A Narrative Review Antibiotics hidradenitis suppurativa acne inversa infections bacteria |
| title | What Do We Know About Bacterial Infections in Hidradenitis Suppurativa?—A Narrative Review |
| title_full | What Do We Know About Bacterial Infections in Hidradenitis Suppurativa?—A Narrative Review |
| title_fullStr | What Do We Know About Bacterial Infections in Hidradenitis Suppurativa?—A Narrative Review |
| title_full_unstemmed | What Do We Know About Bacterial Infections in Hidradenitis Suppurativa?—A Narrative Review |
| title_short | What Do We Know About Bacterial Infections in Hidradenitis Suppurativa?—A Narrative Review |
| title_sort | what do we know about bacterial infections in hidradenitis suppurativa a narrative review |
| topic | hidradenitis suppurativa acne inversa infections bacteria |
| url | https://www.mdpi.com/2079-6382/14/2/142 |
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