Kansui-liquorice enhances the “water-expelling” effect of Gansui Banxia decoction in rats with malignant ascites by targeting the NPs/NPRs/cGMP/PKGⅡ pathway and T cell immunity

Kansui-liquorice enhances the “water-expelling” effect of Gansui Banxia decoction in rats with malignant ascites by targeting the NPs/NPRs/cGMP/PKGⅡ pathway and T cell immunity

Ethnopharmacological relevanceThe combination of Euphorbia kansui Liou ex S.B.Ho (kansui) and Glycyrrhiza uralensis Fisch (liquorice) is contraindicated in Chinese medicine, but whether it can be used in clinical practice remains controversial. The classic formula, Gansui Banxia decoction (GBD), con...

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Bibliographic Details
Main Authors: Min Huo, Haiyan Liu, Shaohong Chen, Lingling Xiu, Xue Yu, Gansheng Zhong
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Pharmacology
Subjects:
kansui-liquorice
Gansui Banxia decoction
network pharmacology
pharmacokinetics
water-expelling
T Cell immunity
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1557717/full
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